Product: HEN2 Antibody
Catalog: DF10046
Description: Rabbit polyclonal antibody to HEN2
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Rabbit, Dog
Mol.Wt.: 15 kDa; 15kD(Calculated).
Uniprot: Q02577
RRID: AB_2840626

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(90%), Bovine(89%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
HEN2 Antibody detects endogenous levels of total HEN2.
RRID:
AB_2840626
Cite Format: Affinity Biosciences Cat# DF10046, RRID:AB_2840626.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

bHLHa34; Class A basic helix-loop-helix protein 34; Helix-loop-helix protein 2; HEN-2; HEN2; HEN2_HUMAN; KIAA0490; Nescient helix loop helix 2; Nhlh2; NSCL-2; NSCL2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Dog
100
Pig
90
Bovine
89
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q02577 As Substrate

Site PTM Type Enzyme
T106 Phosphorylation

Research Backgrounds

Function:

May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Efficient DNA binding requires dimerization with another bHLH protein.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.