CSNK1G3 Antibody - #DF10135

(2)  
Product: CSNK1G3 Antibody
Catalog: DF10135
Description: Rabbit polyclonal antibody to CSNK1G3
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
Mol.Wt.: 51 kDa; 51kD(Calculated).
Uniprot: Q9Y6M4
RRID: AB_2840715

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(89%), Horse(100%), Sheep(90%), Rabbit(100%), Dog(100%), Xenopus(91%)
Clonality:
Polyclonal
Specificity:
CSNK1G3 Antibody detects endogenous levels of total CSNK1G3.
RRID:
AB_2840715
Cite Format: Affinity Biosciences Cat# DF10135, RRID:AB_2840715.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

casein kinase 1 gamma 3; casein kinase I gamma 3; Casein kinase I isoform gamma 3; Casein kinase I isoform gamma-3; CKI-gamma 3; Csnk1g3; CSNK1G3L; KC1G3_HUMAN;

Immunogens

Immunogen:
Uniprot:

Q9Y6M4(KC1G3_HUMAN) >>Visit HPA database.

Gene(ID):
CSNK1G3(1456)
Sequence:
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Rabbit
100
Xenopus
91
Sheep
90
Bovine
89
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y6M4 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S11 Phosphorylation
T29 Phosphorylation
S31 Phosphorylation
S32 Phosphorylation
S34 Phosphorylation
K48 Ubiquitination
K61 Ubiquitination
Y64 Phosphorylation
T65 Phosphorylation
Y68 Phosphorylation
Y87 Phosphorylation
Y90 Phosphorylation
K91 Methylation
Y160 Phosphorylation
K164 Ubiquitination
K176 Ubiquitination
Y192 Phosphorylation
K253 Ubiquitination
T256 Phosphorylation
K263 Ubiquitination
K306 Ubiquitination
S344 Phosphorylation
S345 Phosphorylation
S392 Phosphorylation
S397 Phosphorylation
S398 Phosphorylation
S413 Phosphorylation
T421 Phosphorylation
K430 Ubiquitination
K436 Ubiquitination

Research Backgrounds

Function:

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).

PTMs:

Autophosphorylated.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Monomer.

Family&Domains:

Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

Research Fields

· Environmental Information Processing > Signal transduction > Hedgehog signaling pathway.   (View pathway)

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