RASSF4 Antibody - #DF8711
| Product: | RASSF4 Antibody |
| Catalog: | DF8711 |
| Description: | Rabbit polyclonal antibody to RASSF4 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 36 kDa; 37kD(Calculated). |
| Uniprot: | Q9H2L5 |
| RRID: | AB_2841915 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8711, RRID:AB_2841915.
Fold/Unfold
3830411C14Rik; AD037; AI586137; MGC105606; MGC44914; OTTHUMP00000019493; Ras association (RalGDS/AF 6) domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; Ras association domain family 4; Ras association domain-containing protein 4; RASF4_HUMAN; RASSF 4; Rassf4; RP11-285G1.4; Tumor suppressor RASSF4;
Immunogens
- Q9H2L5 RASF4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H2L5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K21 | Ubiquitination | Uniprot | |
| S91 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| K232 | Methylation | Uniprot | |
| S283 | Phosphorylation | Uniprot |
Research Backgrounds
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Widely expressed. Frequently down-regulated in tumor cell lines.
Interacts directly with activated KRAS in a GTP-dependent manner.
Research Fields
· Environmental Information Processing > Signal transduction > Hippo signaling pathway - multiple species. (View pathway)
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