ACAD11 Antibody - #DF9147
| Product: | ACAD11 Antibody |
| Catalog: | DF9147 |
| Description: | Rabbit polyclonal antibody to ACAD11 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Bovine, Sheep, Dog |
| Mol.Wt.: | 87kDa; 87kD(Calculated). |
| Uniprot: | Q709F0 |
| RRID: | AB_2842343 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9147, RRID:AB_2842343.
Fold/Unfold
5730439E10Rik; 62113 protein; ACAD 11; ACAD-11; Acad11; ACD11_HUMAN; Acyl CoA dehydrogenase family member 11; Acyl Coenzyme A dehydrogenase family member 11; Acyl-CoA dehydrogenase family member 11; AI987948; FLJ12592; MGC150619; Putative acyl CoA dehydrogenase; RGD1306270;
Immunogens
Widely expressed with highest levels in brain followed by liver, heart and kidney.
- Q709F0 ACD11_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKPGATGESDLAEVLPQHKFDSKSLEAYLNQHLSGFGAEREATLTIAQYRAGKSNPTFYLQKGFQTYVLRKKPPGSLLPKAHQIDREFKVQKALFSIGFPVPKPILYCSDTSVIGTEFYVMEHVQGRIFRDLTIPGLSPAERSAIYVATVETLAQLHSLNIQSLQLEGYGIGAGYCKRQVSTWTKQYQAAAHQDIPAMQQLSEWLMKNLPDNDNEENLIHGDFRLDNIVFHPKECRVIAVLDWELSTIGHPLSDLAHFSLFYFWPRTVPMINQGSYSENSGIPSMEELISIYCRCRGINSILPNWNFFLALSYFKMAGIAQGVYSRYLLGNNSSEDSFLFANIVQPLAETGLQLSKRTFSTVLPQIDTTGQLFVQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGLWNLFLPAVSGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTAKI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q709F0 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| S54 | Phosphorylation | Uniprot | |
| Y59 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| R86 | Methylation | Uniprot | |
| Y107 | Phosphorylation | Uniprot | |
| Y324 | Phosphorylation | Uniprot | |
| K378 | Acetylation | Uniprot | |
| K385 | Acetylation | Uniprot | |
| C547 | S-Nitrosylation | Uniprot | |
| T576 | Phosphorylation | Uniprot | |
| R619 | Methylation | Uniprot | |
| K683 | Acetylation | Uniprot | |
| K690 | Methylation | Uniprot | |
| K704 | Acetylation | Uniprot |
Research Backgrounds
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Probably participates to beta-oxydation and energy production but could also play role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain (Probable).
Peroxisome. Mitochondrion membrane.
Note: Has been detected associated with mitochondrial membrane, but no matrix, in kidney and cerebellum, as well as in a neuroblastoma cell line, but not in skin fibroblasts, where it is observed in cytoplasmic vesicles (PubMed:21237683). No mitochondrial targeting signals could be predicted for any known isoform, including a putative isoform starting at Met-316.
Widely expressed with highest levels in brain followed by liver, heart and kidney.
Homodimer.
Belongs to the acyl-CoA dehydrogenase family.
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