ANXA11 Antibody - #DF9215

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Product: ANXA11 Antibody
Catalog: DF9215
Description: Rabbit polyclonal antibody to ANXA11
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 54kDa; 54kD(Calculated).
Uniprot: P50995
RRID: AB_2842411

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(82%)
Clonality:
Polyclonal
Specificity:
ANXA11 Antibody detects endogenous levels of total ANXA11.
RRID:
AB_2842411
Cite Format: Affinity Biosciences Cat# DF9215, RRID:AB_2842411.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

56 kDa autoantigen; Annexin A11; Annexin XI; Annexin-11; AnnexinA11; AnnexinXI; ANX 11; ANX A11; ANX11; ANX11_HUMAN; ANXA 11; ANXA11; Autoantigen 56 kD; Calcyclin associated annexin 50; Calcyclin-associated annexin 50; CAP 50; CAP-50; CAP50; OTTHUMP00000059806;

Immunogens

Immunogen:
Uniprot:

P50995(ANX11_HUMAN) >>Visit HPA database.

Gene(ID):
ANXA11(311)
Sequence:
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGND

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
82
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P50995 As Substrate

Site PTM Type Enzyme
Y53 Phosphorylation
K214 Ubiquitination
K248 Acetylation
K248 Ubiquitination
K252 Ubiquitination
K255 Acetylation
K255 Sumoylation
K255 Ubiquitination
S259 Phosphorylation
K264 Methylation
K264 Ubiquitination
K271 Ubiquitination
T272 Phosphorylation
Y279 Phosphorylation
K282 Acetylation
K282 Sumoylation
K282 Ubiquitination
K286 Ubiquitination
T290 Phosphorylation
C294 S-Nitrosylation
S301 Phosphorylation
K315 Ubiquitination
K320 Ubiquitination
T321 Phosphorylation
R346 Methylation
Y365 Phosphorylation
K378 Sumoylation
K378 Ubiquitination
C384 S-Nitrosylation
R400 Methylation
K408 Acetylation
K408 Ubiquitination
S415 Phosphorylation
K427 Ubiquitination
C428 S-Nitrosylation
K430 Ubiquitination
R439 Methylation
T464 Phosphorylation
R470 Methylation
K479 Acetylation
K479 Ubiquitination
S480 Phosphorylation
Y482 Phosphorylation
S486 Phosphorylation
T489 Phosphorylation
S490 Phosphorylation
Y493 Phosphorylation
K499 Sumoylation
K499 Ubiquitination

Research Backgrounds

Function:

Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.

Subcellular Location:

Cytoplasm. Melanosome. Nucleus envelope. Nucleus>Nucleoplasm. Cytoplasm>Cytoskeleton>Spindle.
Note: Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with S100A6. Interacts with PDCD6 in a calcium-dependent manner. Interacts with KIF23 during cytokinesis.

Family&Domains:

A pair of annexin repeats may form one binding site for calcium and phospholipid.

Belongs to the annexin family.

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