STK25 Antibody - #DF9883
| Product: | STK25 Antibody |
| Catalog: | DF9883 |
| Description: | Rabbit polyclonal antibody to STK25 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog, Chicken |
| Mol.Wt.: | 48 kDa; 48kD(Calculated). |
| Uniprot: | O00506 |
| RRID: | AB_2843077 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9883, RRID:AB_2843077.
Fold/Unfold
C86992; Serine/threonine kinase 25; Serine/threonine kinase 25 (STE20 homolog, yeast); Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a; Serine/threonine kinase 25 (yeast); Serine/threonine protein kinase 25; Serine/threonine-protein kinase 25; SOK 1; SOK-1; SOK1; Ste20 like kinase; Ste20 yeast homolog; Ste20-like; STE20-like kinase; Ste20/oxidant stress response kinase 1; Sterile 20 (oxidant stress response kinase 1); Sterile 20/oxidant stress-response kinase 1; STK25; STK25_HUMAN; Yeast Sps1/Ste20 related kinase 1; YSK 1; YSK1;
Immunogens
Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
- O00506 STK25_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWKSEGHGEESSSEDSDIDGEAEDGEQGPIWTFPPTIRPSPHSKLHKGTALHSSQKPAEPVKRQPRSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVERVQRFSHNRNHLTSTR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00506 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| K22 | Ubiquitination | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| K171 | Ubiquitination | Uniprot | |
| T174 | Phosphorylation | O00506 (STK25) | Uniprot |
| T178 | Phosphorylation | Uniprot | |
| S231 | Phosphorylation | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| K253 | Ubiquitination | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| K335 | Ubiquitination | Uniprot | |
| S342 | Phosphorylation | Uniprot | |
| T360 | Phosphorylation | Uniprot |
PTMs - O00506 As Enzyme
Research Backgrounds
Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.
Cytoplasm. Golgi apparatus.
Note: Localizes to the Golgi apparatus.
Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
Homodimer. Interacts with CTTNBP2NL.
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
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