ARP-1 Antibody - #AF9015
Product: | ARP-1 Antibody |
Catalog: | AF9015 |
Description: | Rabbit polyclonal antibody to ARP-1 |
Application: | WB IF/ICC |
Reactivity: | Human |
Prediction: | Bovine, Dog |
Mol.Wt.: | 45kDa; 46kD(Calculated). |
Uniprot: | P24468 |
RRID: | AB_2843206 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF9015, RRID:AB_2843206.
Fold/Unfold
Apolipoprotein A-I regulatory protein 1; Apolipoprotein AI regulatory protein 1; ARP-1; ARP1; COT2_HUMAN; COUP TF2; COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; NR2F2; Nuclear receptor subfamily 2 group F member 2;
Immunogens
- P24468 COT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P24468 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T39 | Phosphorylation | Uniprot | |
T51 | Phosphorylation | Uniprot | |
K89 | Ubiquitination | Uniprot | |
S112 | Phosphorylation | Uniprot | |
K141 | Methylation | Uniprot | |
K301 | Ubiquitination | Uniprot | |
Y348 | Phosphorylation | Uniprot | |
K362 | Ubiquitination | Uniprot | |
K389 | Ubiquitination | Uniprot | |
T394 | Phosphorylation | Uniprot |
Research Backgrounds
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.
Nucleus.
Ubiquitous.
Interacts with SQSTM1 (By similarity). Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2 (By similarity).
Belongs to the nuclear hormone receptor family. NR2 subfamily.
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