TAB182 Antibody - #AF9207

(2)  
Product: TAB182 Antibody
Catalog: AF9207
Description: Rabbit polyclonal antibody to TAB182
Application: WB IHC IF/ICC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Rabbit, Dog
Mol.Wt.: 150kDa; 182kD(Calculated).
Uniprot: Q9C0C2
RRID: AB_2843397

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(91%), Bovine(82%), Horse(91%), Rabbit(100%), Dog(91%)
Clonality:
Polyclonal
Specificity:
TAB182 Antibody detects endogenous levels of total TAB182.
RRID:
AB_2843397
Cite Format: Affinity Biosciences Cat# AF9207, RRID:AB_2843397.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

182 kDa tankyrase 1 binding protein; 182 kDa tankyrase-1-binding protein; FLJ45975; KIAA1741; TAB182; Tankyrase 1 binding protein 1 182 kDa; Tankyrase 1 binding protein 1; Tankyrase 1 binding protein of 182 kDa; TB182_HUMAN; Tnks1bp1;

Immunogens

Immunogen:
Uniprot:

Q9C0C2(TB182_HUMAN) >>Visit HPA database.

Gene(ID):
TNKS1BP1(85456)
Expression:
Q9C0C2 TB182_HUMAN:

Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.

Sequence:
MKVSTLRESSAMASPLPREMEEELVPTGSEPGDTRAKPPVKPKPRALPAKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMLAGPQPYGGSKRPLPFAPRPAVEASTGGEATQETGKEEAGKEEPPPLTPPARCAAPGGVRKAPAPFRPASERFAATTVEEILAKMEQPRKEVLASPDRLWGSRLTFNHDGSSRYGPRTYGTTTAPRDEDGSTLFRGWSQEGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSELPADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGSPHLHPPDKSSPCHSQLLEAQTPEASQASPCPAVTPSAPSAALPDEGSRHTPSPGLPAEGAPEAPRPSSPPPEVLEPHSLDQPPATSPRPLIEVGELLDLTRTFPSGGEEEAKGDAHLRPTSLVQRRFSEGVLQSPSQDQEKLGGSLAALPQGQGSQLALDRPFGAESNWSLSQSFEWTFPTRPSGLGVWRLDSPPPSPITEASEAAEAAEAGNLAVSSREEGVSQQGQGAGSAPSGSGSSWVQGDDPSMSLTQKGDGESQPQFPAVPLEPLPTTEGTPGLPLQQAEERYESQEPLAGQESPLPLATREAALPILEPVLGQEQPAAPDQPCVLFADAPEPGQALPVEEEAVTLARAETTQARTEAQDLCRASPEPPGPESSSRWLDDLLASPPPSGGGARRGAGAELKDTQSPSTCSEGLLGWSQKDLQSEFGITGDPQPSSFSPSSWCQGASQDYGLGGASPRGDPGLGERDWTSKYGQGAGEGSTREWASRCGIGQEEMEASSSQDQSKVSAPGVLTAQDRVVGKPAQLGTQRSQEADVQDWEFRKRDSQGTYSSRDAELQDQEFGKRDSLGTYSSRDVSLGDWEFGKRDSLGAYASQDANEQGQDLGKRDHHGRYSSQDADEQDWEFQKRDVSLGTYGSRAAEPQEQEFGKSAWIRDYSSGGSSRTLDAQDRSFGTRPLSSGFSPEEAQQQDEEFEKKIPSVEDSLGEGSRDAGRPGERGSGGLFSPSTAHVPDGALGQRDQSSWQNSDASQEVGGHQERQQAGAQGPGSADLEDGEMGKRGWVGEFSLSVGPQREAAFSPGQQDWSRDFCIEASERSYQFGIIGNDRVSGAGFSPSSKMEGGHFVPPGKTTAGSVDWTDQLGLRNLEVSSCVGSGGSSEARESAVGQMGWSGGLSLRDMNLTGCLESGGSEEPGGIGVGEKDWTSDVNVKSKDLAEVGEGGGHSQARESGVGQTDWSGVEAGEFLKSRERGVGQADWTPDLGLRNMAPGAVCSPGESKELGVGQMDWGNNLGLRDLEVTCDPDSGGSQGLRGCGVGQMDWTQDLAPQNVELFGAPSEAREHGVGGVSQCPEPGLRHNGSLSPGLEARDPLEARELGVGETSGPETQGEDYSSSSLEPHPADPGMETGEALSFGASPGRCPARPPPSGSQGLLEEMLAASSSKAVARRESAASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFIEDTEILDSAMYRSRANLGRKRGHRAPVIRPGGTLGLSEAADSDAHLFQDSTEPRASRVPSSDEEVVEEPQSRRTRMSLGTKGLKVNLFPGLSPSALKAKLRPRNRSAEEGELAESKSSQKESAVQRSKSCKVPGLGKPLTLPPKPEKSSGSEGSSPNWLQALKLKKKKV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Pig
91
Horse
91
Dog
91
Bovine
82
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9C0C2 As Substrate

Site PTM Type Enzyme
K2 Methylation
T5 Phosphorylation
S9 Phosphorylation
S10 Phosphorylation
S14 Phosphorylation
K50 Acetylation
K80 Ubiquitination
Y90 Phosphorylation
T131 Phosphorylation P28482 (MAPK1)
S153 Phosphorylation
K173 Methylation
S178 Phosphorylation
S185 Phosphorylation
T188 Phosphorylation
S194 Phosphorylation
Y202 Phosphorylation
S221 Phosphorylation
S228 Phosphorylation
T239 Phosphorylation
S244 Phosphorylation
S260 Phosphorylation
S268 Phosphorylation
S275 Phosphorylation
S279 Phosphorylation
S280 Phosphorylation
S287 Phosphorylation
S295 Phosphorylation
S297 Phosphorylation
S301 Phosphorylation
T351 Phosphorylation
S353 Phosphorylation
S368 Phosphorylation
S369 Phosphorylation
S387 Phosphorylation
T401 Phosphorylation
S406 Phosphorylation
S429 Phosphorylation
S435 Phosphorylation P24941 (CDK2)
S437 Phosphorylation P24941 (CDK2)
S456 Phosphorylation
S494 Phosphorylation
S498 Phosphorylation
T501 Phosphorylation
S504 Phosphorylation
S541 Phosphorylation
S551 Phosphorylation
S560 Phosphorylation
T578 Phosphorylation
Y590 Phosphorylation
S592 Phosphorylation
S601 Phosphorylation
T607 Phosphorylation
T659 Phosphorylation
T663 Phosphorylation
S672 Phosphorylation
S691 Phosphorylation P24941 (CDK2)
S695 Phosphorylation
T710 Phosphorylation
S712 Phosphorylation
S714 Phosphorylation
S717 Phosphorylation
S724 Phosphorylation
S744 Phosphorylation
S753 Phosphorylation
S762 Phosphorylation
Y778 Phosphorylation
S786 Phosphorylation
S792 Phosphorylation
S806 Phosphorylation
K827 Ubiquitination
T833 Phosphorylation
S836 Phosphorylation
S851 Phosphorylation
T854 Phosphorylation
Y855 Phosphorylation
S872 Phosphorylation
T875 Phosphorylation
Y876 Phosphorylation
S877 Phosphorylation
S878 Phosphorylation
S882 Phosphorylation
K890 Ubiquitination
S893 Phosphorylation
Y897 Phosphorylation
S899 Phosphorylation
K911 Ubiquitination
Y918 Phosphorylation
S919 Phosphorylation
S920 Phosphorylation
K932 Ubiquitination
S936 Phosphorylation
T939 Phosphorylation
Y940 Phosphorylation
S942 Phosphorylation
K954 Methylation
K954 Ubiquitination
Y961 Phosphorylation
S962 Phosphorylation
T969 Phosphorylation
S976 Phosphorylation
T979 Phosphorylation
S983 Phosphorylation
S984 Phosphorylation
S987 Phosphorylation
S1004 Phosphorylation
S1008 Phosphorylation
S1013 Phosphorylation
S1024 Phosphorylation
S1029 Phosphorylation
S1031 Phosphorylation
T1032 Phosphorylation P28482 (MAPK1)
R1043 Methylation
S1047 Phosphorylation
S1051 Phosphorylation
S1054 Phosphorylation
S1073 Phosphorylation
S1091 Phosphorylation
S1093 Phosphorylation
S1103 Phosphorylation
S1118 Phosphorylation
S1121 Phosphorylation
Y1122 Phosphorylation
R1131 Methylation
S1133 Phosphorylation
S1138 Phosphorylation
S1140 Phosphorylation
S1141 Phosphorylation
S1158 Phosphorylation
S1178 Phosphorylation
S1181 Phosphorylation
S1182 Phosphorylation
S1195 Phosphorylation
S1199 Phosphorylation
T1206 Phosphorylation
K1234 Ubiquitination
S1248 Phosphorylation
S1253 Phosphorylation
S1261 Phosphorylation
T1282 Phosphorylation
S1297 Phosphorylation
S1301 Phosphorylation
S1328 Phosphorylation
S1331 Phosphorylation
T1345 Phosphorylation
S1371 Phosphorylation
S1383 Phosphorylation
S1385 Phosphorylation
S1405 Phosphorylation
Y1414 Phosphorylation
S1415 Phosphorylation
S1416 Phosphorylation
S1418 Phosphorylation
S1435 Phosphorylation
S1439 Phosphorylation
S1450 Phosphorylation
S1452 Phosphorylation
S1463 Phosphorylation
S1473 Phosphorylation
S1476 Phosphorylation
S1503 Phosphorylation
S1506 Phosphorylation
T1518 Phosphorylation
S1533 Phosphorylation
T1540 Phosphorylation
S1545 Phosphorylation
S1552 Phosphorylation
S1554 Phosphorylation
S1558 Phosphorylation
T1563 Phosphorylation
S1602 Phosphorylation
T1611 Phosphorylation
S1616 Phosphorylation
S1620 Phosphorylation
S1621 Phosphorylation
S1631 Phosphorylation
S1637 Phosphorylation
K1641 Methylation
K1644 Methylation
K1644 Ubiquitination
S1652 Phosphorylation
S1654 Phosphorylation
K1657 Methylation
K1657 Ubiquitination
S1666 Phosphorylation
S1675 Phosphorylation
S1677 Phosphorylation
S1689 Phosphorylation
T1700 Phosphorylation
S1708 Phosphorylation
S1711 Phosphorylation
S1714 Phosphorylation
S1715 Phosphorylation

Research Backgrounds

PTMs:

ADP-ribosylated by TNKS1 (in vitro).

Subcellular Location:

Nucleus. Cytoplasm>Cytoskeleton. Chromosome.
Note: Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.

Subunit Structure:

Binds to the ANK repeat domain of TNKS1 and TNKS2.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.