BCS1L Antibody - #DF12189
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12189, RRID:AB_2844994.
Fold/Unfold
BCS 1; BCS 1L; BCS; BCS1 (yeast homolog) like; BCS1; BCS1 like (S. cerevisiae); BCS1 like; BCS1 like protein; Bjornstad syndrome (pili torti and deafness); BJS; FLNMS; GRACILE; h BCS; H BCS1; Hs.6719; Mitochondrial chaperone BCS1; Mitochondrial complex III assembly; PTD;
Immunogens
- Q9Y276 BCS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPLSDFILALKDNPYFGAGFGLVGVGTALALARKGVQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFVPSPGNHFIWYRGKWIRVERSREMQMIDLQTGTPWESVTFTALGTDRKVFFNILEEARELALQQEEGKTVMYTAVGSEWRPFGYPRRRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNHVDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLRATNQISPAQVQGYFMLYKNDPVGAIHNAESLRR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y276 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| Y181 | Phosphorylation | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| S271 | Phosphorylation | Uniprot | |
| S277 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| K300 | Ubiquitination | Uniprot |
Research Backgrounds
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex.
Mitochondrion inner membrane>Single-pass membrane protein.
Ubiquitous.
Interacts with LETM1.
Belongs to the AAA ATPase family. BCS1 subfamily.
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