Product: TNP1 Antibody
Catalog: DF12335
Description: Rabbit polyclonal antibody to TNP1
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 6-10 kDa; 6kD(Calculated).
Uniprot: P09430
RRID: AB_2845140

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(92%), Horse(100%), Sheep(92%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
TNP1 Antibody detects endogenous levels of total TNP1.
RRID:
AB_2845140
Cite Format: Affinity Biosciences Cat# DF12335, RRID:AB_2845140.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Spermatid nuclear transition protein 1; Spermatid nuclear transition protein1; STP 1; STP-1; STP1; STP1_HUMAN; TNP 1; TNP1; TP 1; TP-1; TP1; Transition protein 1 (during histone to protamine replacement); Transition protein1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P09430 STP1_HUMAN:

Expressed by spermatids (at protein level).

Sequence:
MSTSRKLKSHGMRRSKSRSPHKGVKRGGSKRKYRKGNLKSRKRGDDANRNYRSHL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Rabbit
100
Bovine
92
Sheep
92
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P09430 As Substrate

Site PTM Type Enzyme
S9 Phosphorylation
S19 Phosphorylation
S40 Phosphorylation

Research Backgrounds

Function:

Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

Subcellular Location:

Nucleus. Chromosome.
Note: Loaded onto the nucleosomes of condensing spermatids.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed by spermatids (at protein level).

Family&Domains:

Belongs to the nuclear transition protein 1 family.

Restrictive clause

 

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For Research Use Only.
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