NMD3 Antibody - #DF12672

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Product: NMD3 Antibody
Catalog: DF12672
Description: Rabbit polyclonal antibody to NMD3
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 58 kDa; 58kD(Calculated).
Uniprot: Q96D46
RRID: AB_2845634

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(92%), Bovine(100%), Horse(100%), Sheep(92%), Rabbit(100%), Dog(92%), Chicken(83%), Xenopus(83%)
Clonality:
Polyclonal
Specificity:
NMD3 Antibody detects endogenous levels of total NMD3.
RRID:
AB_2845634
Cite Format: Affinity Biosciences Cat# DF12672, RRID:AB_2845634.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

60S ribosomal export protein NMD3; CGI 07; FLJ21053; hNMD3; NMD3; NMD3 homolog; NMD3 homolog (S. cerevisiae); NMD3 ribosome export adaptor; NMD3, S. cerevisiae, homolog of; NMD3_HUMAN;

Immunogens

Immunogen:
Uniprot:

Q96D46(NMD3_HUMAN) >>Visit HPA database.

Gene(ID):
NMD3(51068)
Sequence:
MEYMAESTDRSPGHILCCECGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWIQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSAIHLIDPNTLQVADIDGSTFWSHPFNSLCHPKQLEEFIVMECSIVQDIKRAAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEHVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARERENMDTDDERQYQDFLEDLEEDEAIRKNVNIYRDSAIPVESDTDDEGAPRISLAEMLEDLHISQDATGEEGASMLT

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Rabbit
100
Pig
92
Sheep
92
Dog
92
Xenopus
83
Chicken
83
Zebrafish
75
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96D46 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S11 Phosphorylation
S25 Phosphorylation
K39 Ubiquitination
S51 Phosphorylation
K84 Ubiquitination
K85 Acetylation
K108 Ubiquitination
K150 Ubiquitination
K202 Ubiquitination
T235 Phosphorylation
Y236 Phosphorylation
Y238 Phosphorylation
S258 Phosphorylation
S337 Phosphorylation
K338 Acetylation
K339 Ubiquitination
K349 Ubiquitination
K357 Ubiquitination
S395 Phosphorylation
R397 Methylation
T433 Phosphorylation
R437 Methylation
Y439 Phosphorylation
K454 Ubiquitination
Y459 Phosphorylation
S462 Phosphorylation
S468 Phosphorylation
T470 Phosphorylation
S479 Phosphorylation
S490 Phosphorylation

Research Backgrounds

Function:

Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.

Subcellular Location:

Cytoplasm. Nucleus.
Note: Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Found in a 60S ribosomal subunit export complex with RAN and XPO1. Interacts with XPO1. Associates with the 60S ribosomal subunit.

Family&Domains:

Belongs to the NMD3 family.

Research Fields

· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.

· Genetic Information Processing > Translation > RNA transport.

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