CSDE1 Antibody - #DF12920

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Product: CSDE1 Antibody
Catalog: DF12920
Description: Rabbit polyclonal antibody to CSDE1
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 89 kDa; 89kD(Calculated).
Uniprot: O75534
RRID: AB_2845881

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(92%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
CSDE1 Antibody detects endogenous levels of total CSDE1.
RRID:
AB_2845881
Cite Format: Affinity Biosciences Cat# DF12920, RRID:AB_2845881.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS;

Immunogens

Immunogen:
Uniprot:

O75534(CSDE1_HUMAN) >>Visit HPA database.

Gene(ID):
CSDE1(7812)
Sequence:
MSFDPNLLHNNGHNGYPNGTSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNLQDLKVGDDVEFEVSSDRRTGKPIAVKLVKIKQEILPEERMNGQVVCAVPHNLESKSPAAPGQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLKKKQARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRNGKEVATDVRLLPQGTVIFEDISIEHFEGTVTKVIPKVPSKNQNDPLPGRIKVDFVIPKELPFGDKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGFGFIKCVDRDVRMFFHFSEILDGNQLHIADEVEFTVVPDMLSAQRNHAIRIKKLPKGTVSFHSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGIIAYDDCGVKLTIAFQAKDVEGSTSPQIGDKVEFSISDKQRPGQQVATCVRLLGRNSNSKRLLGYVATLKDNFGFIETANHDKEIFFHYSEFSGDVDSLELGDMVEYSLSKGKGNKVSAEKVNKTHSVNGITEEADPTIYSGKVIRPLRSVDPTQTEYQGMIEIVEEGDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLGQNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDGIELQAGDEVEFSVILNQRTGKCSACNVWRVCEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPDNSMGFGAERKIRQAGVID

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
92
Xenopus
75
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75534 As Substrate

Site PTM Type Enzyme
S2 Phosphorylation
K32 Ubiquitination
K81 Acetylation
K81 Ubiquitination
K86 Ubiquitination
K91 Sumoylation
K91 Ubiquitination
S116 Phosphorylation
S123 Phosphorylation
S127 Phosphorylation
Y138 Phosphorylation
K166 Ubiquitination
K180 Ubiquitination
K194 Ubiquitination
K207 Ubiquitination
K234 Ubiquitination
K239 Acetylation
K239 Ubiquitination
K273 Ubiquitination
S276 Phosphorylation
K277 Ubiquitination
K288 Ubiquitination
K295 Ubiquitination
K302 Ubiquitination
K307 Ubiquitination
R324 Methylation
K364 Acetylation
K364 Ubiquitination
K415 Ubiquitination
S419 Phosphorylation
S422 Phosphorylation
S424 Phosphorylation
T431 Phosphorylation
K434 Acetylation
K434 Ubiquitination
K442 Ubiquitination
T443 Phosphorylation
T444 Phosphorylation
S445 Phosphorylation
K452 Ubiquitination
T481 Phosphorylation
S482 Phosphorylation
K488 Ubiquitination
K496 Ubiquitination
S514 Phosphorylation
T525 Phosphorylation
K527 Ubiquitination
K578 Ubiquitination
K581 Ubiquitination
S584 Phosphorylation
Y597 Phosphorylation
K600 Ubiquitination
S607 Phosphorylation
K628 Sumoylation
K642 Ubiquitination
K648 Acetylation
K648 Ubiquitination
T677 Phosphorylation
K682 Acetylation
K682 Ubiquitination
Y690 Phosphorylation
K696 Acetylation
K696 Ubiquitination
K697 Acetylation
K697 Ubiquitination
K729 Ubiquitination
K743 Ubiquitination
R749 Methylation
R752 Methylation
K758 Ubiquitination
T761 Phosphorylation
S782 Phosphorylation

Research Backgrounds

Function:

RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of a multi subunit autoregulatory ribonucleoprotein complex (ARC), at least composed of IGF2BP1, PABPC1 and CSDE1. Interacts with STRAP. Part of a complex associated with the FOS mCRD domain and consisting of PABPC1, PAIP1, HNRPD and SYNCRIP. The interaction with PABPC1 is direct and RNA-independent.

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