TGN46 Antibody - #DF13213
| Product: | TGN46 Antibody |
| Catalog: | DF13213 |
| Description: | Rabbit polyclonal antibody to TGN46 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Bovine, Rabbit, Dog |
| Mol.Wt.: | 51kDa; 46kD(Calculated). |
| Uniprot: | O43493 |
| RRID: | AB_2846232 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13213, RRID:AB_2846232.
Fold/Unfold
TGN 46; TGN 51; TGN38; TGN38 homolog; TGN38B; TGN46; TGN48; TGN51; TGOLN2; TGON2_HUMAN; Trans Golgi network integral membrane protein 2; Trans golgi network protein 2; Trans Golgi network protein TGN51; Trans-Golgi network integral membrane protein 2; Trans-Golgi network protein TGN51; TTGN2;
Immunogens
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.
- O43493 TGON2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSKVTRRPKASDYQRLDQKS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43493 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S36 | O-Glycosylation | Uniprot | |
| S41 | O-Glycosylation | Uniprot | |
| T42 | O-Glycosylation | Uniprot | |
| S45 | O-Glycosylation | Uniprot | |
| S47 | O-Glycosylation | Uniprot | |
| S53 | O-Glycosylation | Uniprot | |
| T54 | O-Glycosylation | Uniprot | |
| S56 | O-Glycosylation | Uniprot | |
| T62 | O-Glycosylation | Uniprot | |
| S66 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| S70 | Phosphorylation | Uniprot | |
| S71 | Phosphorylation | Uniprot | |
| T76 | Phosphorylation | Uniprot | |
| T80 | Phosphorylation | Uniprot | |
| S84 | Phosphorylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| S95 | Phosphorylation | Uniprot | |
| S98 | Phosphorylation | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| T118 | O-Glycosylation | Uniprot | |
| T119 | O-Glycosylation | Uniprot | |
| S122 | O-Glycosylation | Uniprot | |
| T123 | O-Glycosylation | Uniprot | |
| S124 | O-Glycosylation | Uniprot | |
| S126 | O-Glycosylation | Uniprot | |
| T132 | O-Glycosylation | Uniprot | |
| T132 | Phosphorylation | Uniprot | |
| S136 | O-Glycosylation | Uniprot | |
| T137 | O-Glycosylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| T202 | O-Glycosylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| S236 | O-Glycosylation | Uniprot | |
| S245 | O-Glycosylation | Uniprot | |
| S245 | Phosphorylation | Uniprot | |
| S263 | O-Glycosylation | Uniprot | |
| S263 | Phosphorylation | Uniprot | |
| S267 | O-Glycosylation | Uniprot | |
| S270 | O-Glycosylation | Uniprot | |
| S290 | O-Glycosylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| T296 | Phosphorylation | Uniprot | |
| S298 | Phosphorylation | Uniprot | |
| T302 | Phosphorylation | Uniprot | |
| S306 | Phosphorylation | Uniprot | |
| T318 | O-Glycosylation | Uniprot | |
| T331 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | Uniprot | |
| S360 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| K426 | Ubiquitination | Uniprot | |
| S428 | Phosphorylation | Uniprot | |
| Y430 | Phosphorylation | Uniprot |
Research Backgrounds
May be involved in regulating membrane traffic to and from trans-Golgi network.
Cell membrane>Single-pass type I membrane protein. Golgi apparatus>trans-Golgi network membrane>Single-pass type I membrane protein.
Note: Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.
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