TTC7A Antibody - #DF13728
Product: | TTC7A Antibody |
Catalog: | DF13728 |
Description: | Rabbit polyclonal antibody to TTC7A |
Application: | WB IHC IF/ICC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
Mol.Wt.: | 96kDa; 96kD(Calculated). |
Uniprot: | Q9ULT0 |
RRID: | AB_2846747 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF13728, RRID:AB_2846747.
Fold/Unfold
KIAA1140; Tetratricopeptide repeat domain 7A; Tetratricopeptide repeat protein 7A; TPR repeat protein 7A; TTC7; Ttc7a; TTC7A_HUMAN;
Immunogens
Expressed in epithelial cells of the intestine, thymus, and pancreas (at protein level).
- Q9ULT0 TTC7A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAKGAHGSYLKVESELERCRAEGHWDRMPELVRQLQTLSMPGGGGNRRGSPSAAFTFPDTDDFGKLLLAEALLEQCLKENHAKIKDSMPLLEKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9ULT0 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K4 | Ubiquitination | Uniprot | |
S9 | Phosphorylation | Uniprot | |
K12 | Ubiquitination | Uniprot | |
S51 | Phosphorylation | Uniprot | |
S53 | Phosphorylation | Uniprot | |
T57 | Phosphorylation | Uniprot | |
K79 | Ubiquitination | Uniprot | |
K103 | Ubiquitination | Uniprot | |
S108 | Phosphorylation | Uniprot | |
S116 | Phosphorylation | Uniprot | |
K157 | Ubiquitination | Uniprot | |
Y160 | Phosphorylation | Uniprot | |
K172 | Ubiquitination | Uniprot | |
S182 | Phosphorylation | Uniprot | |
S185 | Phosphorylation | Uniprot | |
K259 | Ubiquitination | Uniprot | |
K274 | Ubiquitination | Uniprot | |
K280 | Ubiquitination | Uniprot | |
K326 | Ubiquitination | Uniprot | |
Y396 | Phosphorylation | Uniprot | |
S400 | Phosphorylation | Uniprot | |
K516 | Ubiquitination | Uniprot | |
K560 | Ubiquitination | Uniprot | |
S647 | Phosphorylation | Uniprot | |
K655 | Ubiquitination | Uniprot | |
K656 | Ubiquitination | Uniprot | |
S658 | Phosphorylation | Uniprot | |
S672 | Phosphorylation | Uniprot | |
S678 | Phosphorylation | Uniprot | |
S679 | Phosphorylation | Uniprot | |
S690 | Phosphorylation | Uniprot | |
T693 | Phosphorylation | Uniprot | |
S697 | Phosphorylation | Uniprot | |
K758 | Ubiquitination | Uniprot | |
K765 | Ubiquitination | Uniprot | |
K769 | Ubiquitination | Uniprot | |
K795 | Ubiquitination | Uniprot | |
K800 | Ubiquitination | Uniprot |
Research Backgrounds
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions (By similarity).
Cytoplasm. Cell membrane.
Note: Localizes to the cytosol and is recruited to the plasma membrane following interaction with EFR3 (EFR3A or EFR3B).
Expressed in epithelial cells of the intestine, thymus, and pancreas (at protein level).
Component of a phosphatidylinositol 4-kinase (PI4K) complex, composed of PI4KA, EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B). Interacts with PI4KA, interaction is direct (By similarity). Interacts with EFR3 (EFR3A or EFR3B), interaction is direct (By similarity). Interacts with FAM126 (FAM126A or FAM126B), interaction is direct (By similarity). Association with the PI4K complex is strongly reduced by TMEM150A (By similarity).
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