RPS19BP1 Antibody - #DF15462

Product: RPS19BP1 Antibody
Catalog: DF15462
Description: Rabbit polyclonal antibody to RPS19BP1
Application: ELISA(peptide)
Reactivity: Human
Mol.Wt.: 15kD(Calculated).
Uniprot: Q86WX3

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
RPS19BP1 Antibody detects endogenous levels of RPS19BP1.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

40S ribosomal protein S19 binding protein 1; 40S ribosomal protein S19-binding protein 1; Active regulator of SIRT1; AROS; AROS_HUMAN; Homolog of mouse S19 binding protein; Ribosomal protein S19 binding protein 1; RPS19 binding protein 1; RPS19-binding protein 1; RPS19BP1; S19BP;

Immunogens

Immunogen:

A synthesized peptide derived from human RPS19BP1.

Uniprot:

Q86WX3(AROS_HUMAN) >>Visit HPA database.

Gene(ID):
RPS19BP1(91582)
Expression:
Q86WX3 AROS_HUMAN:

Widely expressed (at protein level).

Sequence:
MSAALLRRGLELLAASEAPRDPPGQAKPRGAPVKRPRKTKAIQAQKLRNSAKGKVPKSALDEYRKRECRDHLRVNLKFLTRTRSTVAESVSQQILRQNRGRKACDRPVAKTKKKKAEGTVFTEEDFQKFQQEYFGS

Research Backgrounds

Function:

Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity.

PTMs:

Citrullinated by PADI4.

Subcellular Location:

Nucleus>Nucleolus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed (at protein level).

Subunit Structure:

Interacts with RPS19 (By similarity). Interacts with SIRT1.

Family&Domains:

Belongs to the AROS family.

Restrictive clause

 

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