DNAJC24 Antibody - #DF15749

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Product: DNAJC24 Antibody
Catalog: DF15749
Description: Rabbit polyclonal antibody to DNAJC24
Application: WB IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 17kD(Calculated).
Uniprot: Q6P3W2

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
DNAJC24 Antibody detects endogenous levels of DNAJC24.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1700030A21Rik; 2610027M02Rik; AV066965; AW240712; CSL type zinc finger containing protein 3; CSL-type zinc finger-containing protein 3; DJC24_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 24; DnaJ homolog subfamily C member 24; DNAJC24; DPH4 homolog (JJJ3, S. cerevisiae); DPH4 homolog; DPH4, JJJ3 homolog; JJJ3; MmDjC7; RGD1564710; RP23-232D1.6; ZCSL3; Zinc finger, CSL domain containing 3; Zinc finger, CSL type containing 3;

Immunogens

Immunogen:

A synthesized peptide derived from human DNAJC24.

Uniprot:

Q6P3W2(DJC24_HUMAN) >>Visit HPA database.

Gene(ID):
DNAJC24(120526)
Sequence:
MMAVEQMPKKDWYSILGADPSANISDLKQKYQKLILMYHPDKQSTDVPAGTVEECVQKFIEIDQAWKILGNEETKREYDLQRCEDDLRNVGPVDAQVYLEEMSWNEGDHSFYLSCRCGGKYSVSKDEAEEVSLISCDTCSLIIELLHYN

Research Backgrounds

Function:

Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

Subcellular Location:

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Monomer and homooligomer. Iron binding promotes oligomerization.

Family&Domains:

The DPH-type metal-binding (MB) domain can bind either zinc or iron ions.

Belongs to the DPH4 family.

Restrictive clause

 

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