CSTF1 Antibody - #DF3241
| Product: | CSTF1 Antibody |
| Catalog: | DF3241 |
| Description: | Rabbit polyclonal antibody to CSTF1 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 48 KD; 48kD(Calculated). |
| Uniprot: | Q05048 |
| RRID: | AB_2835621 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF3241, RRID:AB_2835621.
Fold/Unfold
CF 1 50 kDa subunit; CF-1 50 kDa subunit; Cleavage stimulation factor 50 kDa subunit; Cleavage stimulation factor 50kDa subunit; Cleavage stimulation factor; Cleavage stimulation factor subunit 1; Cleavage stimulation factor, 3 prime pre RNA, subunit 1, 50 kD; cleavage stimulation factor, 3' pre RNA, subunit 1, 50kD; cleavage stimulation factor, 3' pre RNA, subunit 1, 50kDa; CstF 50; CSTF 50 kDa subunit; CstF-50; CSTF1; CSTF1_HUMAN; CstFp50; OTTHUMP00000031332;
Immunogens
- Q05048 CSTF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q05048 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T63 | Phosphorylation | Uniprot | |
| Y67 | Phosphorylation | Uniprot | |
| Y195 | Phosphorylation | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| K316 | Ubiquitination | Uniprot | |
| K319 | Ubiquitination | Uniprot | |
| K326 | Ubiquitination | Uniprot | |
| T364 | Phosphorylation | Uniprot | |
| Y367 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot |
Research Backgrounds
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.
The N-terminus is blocked.
Nucleus.
Homodimer. The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). Interacts (via repeats WD) directly with CSTF3. Interacts (via repeat WD6) with BARD1. Interacts with ERCC6.
N-terminus mediates homodimerization.
Research Fields
· Genetic Information Processing > Translation > mRNA surveillance pathway.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.