Product: CGREF1 Antibody
Catalog: DF3912
Description: Rabbit polyclonal antibody to CGREF1
Application: WB IHC IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 31 KD; 33kD(Calculated).
Uniprot: Q99674
RRID: AB_2836265

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
CGREF1 Antibody detects endogenous levels of total CGREF1.
RRID:
AB_2836265
Cite Format: Affinity Biosciences Cat# DF3912, RRID:AB_2836265.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cell growth regulator with EF hand domain 1; Cell growth regulator with EF hand domain protein 1; Cell growth regulatory gene 11; Cell growth regulatory gene 11 protein; CGR 11; CGR11; CGRE1_HUMAN; CGREF 1; CGREF1; Hydrophobestin;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MLPLTMTVLILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGRTEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVDKVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDEI

PTMs - Q99674 As Substrate

Site PTM Type Enzyme
T61 O-Glycosylation
S69 O-Glycosylation
S159 O-Glycosylation
S170 O-Glycosylation
S175 O-Glycosylation
T181 O-Glycosylation

Research Backgrounds

Function:

Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines.

PTMs:

Probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides.

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Both EF-hands are required for function.

Restrictive clause

 

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