CST11 Antibody - #DF3975

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Product: CST11 Antibody
Catalog: DF3975
Description: Rabbit polyclonal antibody to CST11
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 17 KD; 17kD(Calculated).
Uniprot: Q9H112
RRID: AB_2836335

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
CST11 Antibody detects endogenous levels of total CST11.
RRID:
AB_2836335
Cite Format: Affinity Biosciences Cat# DF3975, RRID:AB_2836335.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cst11; CST11_HUMAN; CST8L; cystatin 11; cystatin related epididymal specific protein; Cystatin-11; dJ322G13.6; SC13; SC13delta;

Immunogens

Immunogen:
Uniprot:

Q9H112(CST11_HUMAN) >>Visit HPA database.

Gene(ID):
CST11(140880)
Expression:
Q9H112 CST11_HUMAN:

Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level).

Sequence:
MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRIFRVLKVQRQVTDHLEYHLNVEMQWTTCQKPETTNCVPQERELHKQVNCFFSVFAVPWFEQYKILNKSCSSD

PTMs - Q9H112 As Substrate

Site PTM Type Enzyme
T18 Phosphorylation
R27 Methylation

Research Backgrounds

Function:

Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization.

Subcellular Location:

Secreted.
Note: Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level).

Family&Domains:

Belongs to the cystatin family.

Restrictive clause

 

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