Product: RASL10A Antibody
Catalog: DF4390
Description: Rabbit polyclonal antibody to RASL10A
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Dog
Mol.Wt.: 30 KD; 23kD(Calculated).
Uniprot: Q92737
RRID: AB_2836745

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
RASL10A Antibody detects endogenous levels of total RASL10A.
RRID:
AB_2836745
Cite Format: Affinity Biosciences Cat# DF4390, RRID:AB_2836745.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Ras like protein family member 10A; Ras like protein RRP22; RAS like, family 10, member A; RAS related on chromosome 22; Ras related protein on chromosome 22; Ras related protein on chromosome 22 homolog; Ras-like protein family member 10A; Ras-like protein RRP22; Ras-related protein on chromosome 22; RASL 10A; Rasl10a; RASL10A protein; Rasl10a RAS like, family 10, member A; RRP 22; RRP22; RSLAA_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q92737 RSLAA_HUMAN:

Expression appears to be strictly limited to the central nervous system.

Sequence:
MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
75
Xenopus
71
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

Research Backgrounds

Function:

Potent inhibitor of cellular proliferation.

PTMs:

Isoprenylation is essential for nucleolar localization, and the proliferation-inhibiting activity of RASL10A.

Subcellular Location:

Cell membrane>Lipid-anchor>Cytoplasmic side. Nucleus>Nucleolus.
Note: May cycle in and out of the nucleolus in a GTP-dependent manner.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expression appears to be strictly limited to the central nervous system.

Family&Domains:

Belongs to the small GTPase superfamily. Ras family.

Restrictive clause

 

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For Research Use Only.
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