SLC6A1 Antibody - #DF4510
*The optimal dilutions should be determined by the end user.
Cite Format: Affinity Biosciences Cat# DF4510, RRID:AB_2836861.
GABATHG; GABATR; GABT 1; GABT1; GAT-1; GAT1; SC6A1_HUMAN; Slc6a1; Sodium and chloride dependent GABA transporter 1; Sodium- and chloride-dependent GABA transporter 1; Solute carrier family 6 (neurotransmitter transporter GABA) member 1; Solute carrier family 6 member 1;
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P30531 As Substrate
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
Cell membrane>Multi-pass membrane protein. Membrane>Multi-pass membrane protein. Cell junction>Synapse>Presynapse.
Note: Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity).
Interacts with MPP5.
The PDZ domain-binding motif is involved in the interaction with MPP5.
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.
· Organismal Systems > Nervous system > GABAergic synapse.
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