ZADH2 Antibody - #DF4640
| Product: | ZADH2 Antibody |
| Catalog: | DF4640 |
| Description: | Rabbit polyclonal antibody to ZADH2 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse, Dog, Chicken, Xenopus |
| Mol.Wt.: | 45 KD; 40kD(Calculated). |
| Uniprot: | Q8N4Q0 |
| RRID: | AB_2836931 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4640, RRID:AB_2836931.
Fold/Unfold
MGC32469; MGC45594; Zinc binding alcohol dehydrogenase domain containing 2; Zinc binding alcohol dehydrogenase domain containing protein 2;
Immunogens
- Q8N4Q0 PTGR3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLRLVPTGARAIVDMSYARHFLDFQGSAIPQAMQKLVVTRLSPNFREAVTLSRDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIFRAVNYMYMGKNTGKIVVELPHSVNSKL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8N4Q0 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K174 | Acetylation | Uniprot | |
| K174 | Methylation | Uniprot | |
| K175 | Acetylation | Uniprot | |
| K194 | Acetylation | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| K225 | Ubiquitination | Uniprot | |
| S299 | Phosphorylation | Uniprot |
Research Backgrounds
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Peroxisome.
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
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