STK17B Antibody - #DF4777
| Product: | STK17B Antibody |
| Catalog: | DF4777 |
| Description: | Rabbit polyclonal antibody to STK17B |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Sheep, Dog |
| Mol.Wt.: | 45 KD; 42kD(Calculated). |
| Uniprot: | O94768 |
| RRID: | AB_2837131 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4777, RRID:AB_2837131.
Fold/Unfold
DAP kinase related apoptosis inducing protein; DAP kinase related apoptosis inducing protein kinase 2; DAP kinase-related apoptosis-inducing protein kinase 2; Death associated protein kinase related 2; DRAK 2; DRAK2; Serine/threonine kinase 17b; Serine/threonine kinase 17b apoptosis inducing; Serine/threonine protein kinase 17B; Serine/threonine-protein kinase 17B; ST17B_HUMAN; STK 17B; Stk17b;
Immunogens
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
- O94768 ST17B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O94768 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | O94768 (STK17B) | Uniprot |
| S12 | Phosphorylation | O94768 (STK17B) | Uniprot |
| K37 | Ubiquitination | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| K53 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| K65 | Ubiquitination | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| T333 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | P05129 (PRKCG) | Uniprot |
| K352 | Ubiquitination | Uniprot |
PTMs - O94768 As Enzyme
Research Backgrounds
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Autophosphorylated.
Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment.
Note: Colocalizes with STK17B at the plasma membrane.
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Interacts with CHP1; the interaction induces CHP1 to translocate from the Golgi to the nucleus.
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
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