FAM81B Antibody - #DF7063
(8)
| Product: | FAM81B Antibody |
| Catalog: | DF7063 |
| Description: | Rabbit polyclonal antibody to FAM81B |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 52kDa; 52kD(Calculated). |
| Uniprot: | Q96LP2 |
| RRID: | AB_2839019 |
Related Downloads
Protocols
Product Info
Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:100
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
EGF Antibody detects endogenous levels of total FAM81B.
RRID:
AB_2839019
Cite Format: Affinity Biosciences Cat# DF7063, RRID:AB_2839019.
Cite Format: Affinity Biosciences Cat# DF7063, RRID:AB_2839019.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
FA81B_HUMAN; FAM81B; Family with sequence similarity 81, member B; FLJ25333; Hypothetical protein LOC153643; Protein FAM81B;
Immunogens
Immunogen:
A synthesized peptide derived from human FAM81B, corresponding to a region within N-terminal amino acids.
Uniprot:
Gene(ID):
Description:
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
Sequence:
- Q96LP2 FA81B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQLQFLGTLASSEKRKKSQRLFFKNIKSTKNKAGKASIMSSDTNVNKSASPTATAEEQPVEPDGPLPGSDNNQEKKVRLSPAKMSTKNSTDLVEYVDKSHAFLPIIPNTQRGQLEDRLNNQARTIAFLLEQAFRIKEDISACLQGTHGFRKEESLARKLLESHIQTITSIVKKLSQNIEILEDQIRARDQAATGTNFAVHEINIKHLQGVGDLRGRVARCDSSIVKLSGDIHLFRQEHRQIEKAIQEFVPALETLSKNLDMKVMQLLGKIETASSEQTSNLKMVQGDYRHEMNLLEFKFHSLSSNLYEEVENNKKWTENQFLKYRKDHLGHINECLKVLQEKLEKSENKMEEKLLQLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELETMQNEYQSGFKSIHDSLSSLQQIQKTKMDLEKYKVQKDLKKLQRKIVELQEV
PTMs - Q96LP2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S28 | Phosphorylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| S99 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S358 | Phosphorylation | Uniprot | |
| S359 | Phosphorylation | Uniprot | |
| T372 | Phosphorylation | Uniprot | |
| K386 | Acetylation | Uniprot |
Research Backgrounds
Family&Domains:
Belongs to the FAM81 family.
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For Research Use Only.
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