AL2S7 Antibody | Affinity Biosciences

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Western blot analysis of extracts from Mouse kidney, using AL2S7 Antibody.

Product:	AL2S7 Antibody
Catalog:	AF0509
Description:	Rabbit polyclonal antibody to AL2S7
Application:	WB IF/ICC
Reactivity:	Human, Mouse
Prediction:	Pig, Sheep, Rabbit, Dog
Mol.Wt.:	46kDa; 49kD(Calculated).
Uniprot:	Q96Q40
RRID:	AB_2834303

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse

Prediction:

Pig(82%), Sheep(91%), Rabbit(82%), Dog(100%)

Clonality:

Polyclonal

Specificity:

AL2S7 Antibody detects endogenous levels of total AL2S7.

RRID:

AB_2834303
Cite Format: Affinity Biosciences Cat# AF0509, RRID:AB_2834303.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

A2S7; AL2S7; ALS2CR7; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7; CDK15; CDK15_HUMAN; Cell division protein kinase 15; Cyclin-dependent kinase 15; EC 2.7.11.22; PFTAIRE protein kinase 2; PFTAIRE2; PFTK2; Serine/threonine protein kinase ALS2CR7; Serine/threonine protein kinase PFTAIRE 2; Serine/threonine-protein kinase ALS2CR7; Serine/threonine-protein kinase PFTAIRE-2;

Immunogens

Immunogen:

Uniprot:

Q96Q40(CDK15_HUMAN) >>Visit HPA database.

Gene(ID):

CDK15(65061)

Description:

PFTAIRE2 is a CMGC kinase of the CDK family.

Sequence:

Q96Q40 CDK15_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Dog

100

Sheep

Pig

Rabbit

Chicken

Horse

Bovine

Xenopus

Zebrafish

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96Q40 As Substrate

Q96Q40

Site	PTM Type	Source
K108	Ubiquitination	Uniprot
Y114	Phosphorylation	Uniprot
Y118	Phosphorylation	Uniprot
T170	Phosphorylation	Uniprot
K239	Ubiquitination	Uniprot
T343	Phosphorylation	Uniprot

Research Backgrounds

Q96Q40_CDK15_HUMAN

Function:

Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.

Family&Domains:

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

AL2S7 Antibody - #AF0509