mGluR8 Antibody - #AF0172
*The optimal dilutions should be determined by the end user.
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0172, RRID:AB_2833365.
FLJ41058; GLUR8; Glutamate receptor metabotropic 8; GPRC1H; GRM8; GRM8_HUMAN; Metabotropic glutamate receptor 8; MGC126724; mGlu8; mGluR8;
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00222 As Substrate
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cell membrane>Multi-pass membrane protein.
Interacts with PICK1.
Belongs to the G-protein coupled receptor 3 family.
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