ZNHIT1 Antibody - #DF10015
| Product: | ZNHIT1 Antibody |
| Catalog: | DF10015 |
| Description: | Rabbit polyclonal antibody to ZNHIT1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 18 kDa; 18kD(Calculated). |
| Uniprot: | O43257 |
| RRID: | AB_2840595 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10015, RRID:AB_2840595.
Fold/Unfold
CG1I; CGBP1; Cyclin G1 binding protein 1; p18 Hamlet; Zinc finger HIT domain containing protein 1; Zinc finger protein subfamily 4A member 1; zinc finger, HIT type 1; ZNFN4A1;
Immunogens
Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
- O43257 ZNHI1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVEKKTSVRSQDPGQRRVLDRAARQRRINRQLEALENDNFQDDPHAGLPQLGKRLPQFDDDADTGKKKKKTRGDHFKLRFRKNFQALLEEQNLSVAEGPNYLTACAGPPSRPQRPFCAVCGFPSPYTCVSCGARYCTVRCLGTHQETRCLKWTV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43257 As Substrate
Research Backgrounds
Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity.
Phosphorylated on Thr by MAPK11 or MAPK14.
Stres-induced ZNHIT1 is mainly regulated at the level of protein.
Nucleus.
Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. Interacts with NR1D1 and NR2D2. Interacts (via HIT-type zinc finger) with the RUVBL1/ RUVBL2 complex in the presence of ADP.
Belongs to the ZNHIT1 family.
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