MAGEA12 Antibody - #DF10034
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10034, RRID:AB_2840614.
Fold/Unfold
Cancer/testis antigen 1.12; Cancer/testis antigen family 1 member 12; CT1.12; MAGAC_HUMAN; MAGE 12 antigen; MAGE-12 antigen; MAGE12; MAGE12 antigen; MAGE12F; MAGE12F antigen; MAGEA12; Melanoma antigen family A 12; Melanoma associated antigen 12; Melanoma-associated antigen 12;
Immunogens
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
- P43365 MAGAC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPLEQRSQHCKPEEGLEAQGEALGLVGAQAPATEEQETASSSSTLVEVTLREVPAAESPSPPHSPQGASTLPTTINYTLWSQSDEGSSNEEQEGPSTFPDLETSFQVALSRKMAELVHFLLLKYRAREPFTKAEMLGSVIRNFQDFFPVIFSKASEYLQLVFGIEVVEVVRIGHLYILVTCLGLSYDGLLGDNQIVPKTGLLIIVLAIIAKEGDCAPEEKIWEELSVLEASDGREDSVFAHPRKLLTQDLVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHLLKISGGPHISYPPLHEWAFREGEE
PTMs - P43365 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K132 | Ubiquitination | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| K292 | Ubiquitination | Uniprot |
Research Backgrounds
Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines.
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
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