Product: MAGB2 Antibody
Catalog: DF10035
Description: Rabbit polyclonal antibody to MAGB2
Application: WB
Reactivity: Human
Mol.Wt.: 35 kDa; 35kD(Calculated).
Uniprot: O15479
RRID: AB_2840615

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
MAGB2 Antibody detects endogenous levels of total MAGB2.
RRID:
AB_2840615
Cite Format: Affinity Biosciences Cat# DF10035, RRID:AB_2840615.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cancer/testis antigen 3.2; Cancer/testis antigen family 3, member 2; CT3.2; DAM6; DSS AHC critical interval MAGE superfamily 6; DSS/AHC critical interval gene, from MAGE superfamily, 6; MAGE B2 antigen; MAGE XP 2; MAGE XP 2 antigen; Mage-b2; Mage-rs2; melanoma antigen family B, 2; Melanoma antigen, family B, 1; Melanoma associated antigen B2; MGC2643; MGC26438; Smage-2 protein; Smage2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O15479 MAGB2_HUMAN:

Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types.

Sequence:
MPRGQKSKLRAREKRRKARDETRGLNVPQVTEAEEEEAPCCSSSVSGGAASSSPAAGIPQEPQRAPTTAAAAAAGVSSTKSKKGAKSHQGEKNASSSQASTSTKSPSEDPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFPEILKKASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGVIFLNGNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPRFQFLWGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDEEKAGV

PTMs - O15479 As Substrate

Site PTM Type Enzyme
S42 Phosphorylation
S44 Phosphorylation
S51 Phosphorylation
S53 Phosphorylation
S77 Phosphorylation
S78 Phosphorylation
K80 Ubiquitination
S81 Phosphorylation
K92 Ubiquitination
S95 Phosphorylation
K104 Ubiquitination
S105 Phosphorylation
K114 Ubiquitination
S117 Phosphorylation
Y124 Phosphorylation
S131 Phosphorylation
K134 Ubiquitination
K139 Ubiquitination
K154 Ubiquitination
K250 Ubiquitination
K256 Ubiquitination
K261 Ubiquitination
K285 Ubiquitination
K287 Ubiquitination
K294 Ubiquitination
K312 Acetylation
K312 Ubiquitination
K316 Ubiquitination

Research Backgrounds

Function:

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.

Tissue Specificity:

Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types.

Subunit Structure:

Interacts with TRIM28.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.