Product: MAGD2 Antibody
Catalog: DF10040
Description: Rabbit polyclonal antibody to MAGD2
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Horse, Rabbit, Dog
Mol.Wt.: 65 kDa; 65kD(Calculated).
Uniprot: Q9UNF1
RRID: AB_2840620

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Horse(83%), Rabbit(83%), Dog(82%)
Clonality:
Polyclonal
Specificity:
MAGD2 Antibody detects endogenous levels of total MAGD2.
RRID:
AB_2840620
Cite Format: Affinity Biosciences Cat# DF10040, RRID:AB_2840620.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

BCG 1; HCA10; JCL 1; MAGE D; MAGE D2 antigen; Melanoma antigen family D 2; Melanoma associated antigen D2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9UNF1 MAGD2_HUMAN:

Widely expressed. In the developing and adult kidney, expressed in the thick ascending limb of the loop of Henle and the distal convoluted tubules outside the loop.

Sequence:
MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKALEVSEDVKVSKASGVSKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGACGFSYK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
83
Horse
83
Dog
82
Sheep
75
Bovine
67
Pig
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UNF1 As Substrate

Site PTM Type Enzyme
S2 Acetylation
S2 Phosphorylation
T4 Phosphorylation
S5 Phosphorylation
S7 Phosphorylation
T12 Phosphorylation
S19 Phosphorylation
T42 Phosphorylation
S46 Phosphorylation
S52 O-Glycosylation
S61 Phosphorylation
T72 Phosphorylation
T81 Phosphorylation
T87 Phosphorylation
S101 Phosphorylation
T106 Phosphorylation
K133 Sumoylation
S146 Phosphorylation
S157 Phosphorylation
S162 Phosphorylation
S190 Phosphorylation
S191 Phosphorylation
S194 Phosphorylation
S197 Phosphorylation
T199 Phosphorylation
T200 Phosphorylation
S206 Phosphorylation
K207 Ubiquitination
S212 Phosphorylation
S218 Phosphorylation
R219 Methylation
S244 Phosphorylation
S247 Phosphorylation
K261 Ubiquitination
S264 Phosphorylation
S265 Phosphorylation
K288 Ubiquitination
K293 Ubiquitination
K297 Ubiquitination
K301 Ubiquitination
S303 Phosphorylation
K311 Ubiquitination
Y313 Phosphorylation
K330 Ubiquitination
K337 Ubiquitination
K341 Ubiquitination
K397 Ubiquitination
K414 Ubiquitination
K422 Ubiquitination
K424 Ubiquitination
Y428 Phosphorylation
Y439 Phosphorylation
Y448 Phosphorylation
Y449 Phosphorylation
K453 Methylation
K458 Ubiquitination
K462 Ubiquitination
K466 Ubiquitination
K469 Ubiquitination
K484 Ubiquitination
K494 Ubiquitination
K528 Ubiquitination
K538 Ubiquitination
K540 Ubiquitination

Research Backgrounds

Function:

Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule.

Tissue Specificity:

Widely expressed. In the developing and adult kidney, expressed in the thick ascending limb of the loop of Henle and the distal convoluted tubules outside the loop.

Subunit Structure:

Interacts with GNAS. May interact with DNAJB1.

Restrictive clause

 

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For Research Use Only.
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