AKAP4 Antibody - #DF10048
| Product: | AKAP4 Antibody |
| Catalog: | DF10048 |
| Description: | Rabbit polyclonal antibody to AKAP4 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Dog |
| Mol.Wt.: | 94 kDa; 94kD(Calculated). |
| Uniprot: | Q5JQC9 |
| RRID: | AB_2840628 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10048, RRID:AB_2840628.
Fold/Unfold
A kinase (PRKA) anchor protein 4; A kinase anchor protein 4; A kinase anchor protein 82 kDa; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; AKAP 4; AKAP 82; AKAP-4; AKAP4; AKAP4_HUMAN; AKAP82; FSC 1; FSC1; hAKAP 82; hAKAP82; HI; Major sperm fibrous sheath protein; p82; PRKA 4; PRKA4; Protein kinase A anchoring protein 4; Protein kinase A-anchoring protein 4; Testis specific gene HI;
Immunogens
- Q5JQC9 AKAP4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMAYSDTTMMSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDAASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQKYALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMTAAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKLEGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKSFLYSELSNKSKSGDKQMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGKPIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNATDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDKGKMKSDPCKSLTSAEKVGEHILKEGLTIWNQKQGNSCKVATKACSNKDEKGEKINASTDSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKALSVKQLESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENKCSEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYSNDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQAVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPDEAVGKVARKQLLDWLLANL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5JQC9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S19 | Phosphorylation | Uniprot | |
| Y57 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| S250 | Phosphorylation | Uniprot | |
| T265 | Phosphorylation | Uniprot | |
| S268 | Phosphorylation | Uniprot | |
| S272 | Phosphorylation | Uniprot | |
| T289 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot | |
| S300 | Phosphorylation | Uniprot | |
| Y303 | Phosphorylation | Uniprot | |
| S304 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| Y336 | Phosphorylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| T420 | Phosphorylation | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| T441 | Phosphorylation | Uniprot | |
| S447 | Phosphorylation | Uniprot | |
| Y448 | Phosphorylation | Uniprot | |
| S450 | Phosphorylation | Uniprot | |
| S464 | Phosphorylation | Uniprot | |
| S484 | Phosphorylation | Uniprot | |
| S489 | Phosphorylation | Uniprot | |
| T491 | Phosphorylation | Uniprot | |
| S492 | Phosphorylation | Uniprot | |
| S536 | Phosphorylation | Uniprot | |
| S539 | Phosphorylation | Uniprot | |
| Y554 | Phosphorylation | Uniprot | |
| T557 | Phosphorylation | Uniprot | |
| T565 | Phosphorylation | Uniprot | |
| S573 | Phosphorylation | Uniprot | |
| T574 | Phosphorylation | Uniprot | |
| S665 | Phosphorylation | Uniprot | |
| S667 | Phosphorylation | Uniprot | |
| Y792 | Phosphorylation | Uniprot |
Research Backgrounds
Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
Cell projection>Cilium>Flagellum.
Note: Localizes to the principle piece of the sperm flagellum.
Testis specific; only expressed in round spermatids.
Interacts with PRKAR1A and PRKAR2A. Interacts with ENO4.
RI-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
Belongs to the AKAP110 family.
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