FBF1 Antibody - #DF10103

(3)  
Product: FBF1 Antibody
Catalog: DF10103
Description: Rabbit polyclonal antibody to FBF1
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Horse, Dog, Xenopus
Mol.Wt.: 125 kDa; 125kD(Calculated).
Uniprot: Q8TES7
RRID: AB_2840683

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Horse(100%), Dog(83%), Xenopus(83%)
Clonality:
Polyclonal
Specificity:
FBF1 Antibody detects endogenous levels of total FBF1.
RRID:
AB_2840683
Cite Format: Affinity Biosciences Cat# DF10103, RRID:AB_2840683.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

ALB; Fas (TNFRSF6) binding factor 1; Fas binding protein 1; fas-binding factor 1; FBF 1; FBF1; FLJ00103; KIAA1863; Protein albatross;

Immunogens

Immunogen:
Uniprot:

Q8TES7(FBF1_HUMAN) >>Visit HPA database.

Gene(ID):
FBF1(85302)
Expression:
Q8TES7 FBF1_HUMAN:

Present in various epithelial cells (at protein level).

Sequence:
MAPKTKKGCKVTLPEKPVKLASHTRDTTGVSQMFPSSKARTKSLLGDDVFSTMAGLEEADAEVSGISEADPQALLQAMKDLDGMDADILGLKKSNSAPSKKAAKDPGKGELPNHPKPAGGAIPTKKSLPSPSSSGHQNRRFSSEDLEDPLRGLLSYDEGGITKQPPVTQSKTASDKSPSTVRDQGPSIPLTPGDTPIRKKEELLFDDGDDIMATLGFGDSPKAEKRQIGDQEGPRPARSTLDELLGRGMATKLLARPGTGEHREFKLDKKYQRPQDSEDMWGDEDFTFGAYQPTVVSSEGRQSRRQSVSRFFADSGADPKGEPGSKQSPPMASSPIQPRKGGADWLGLKDEDLDLFPASPTREAHRESSVPVTPSVPPPASQHSTPAGLPPSRAKPPTEGAGSPAKASQASKLRASKEEKEDWLSHALSRKKSQGLAREQHAGTSEGLHLAGTAGHPPSGSQPLTSTQGLEHAAAGGSSGTTARERPCVRPGVSGSPVTQNHAASALPTGSPKRGTAPGDLSATEPATCFPSTQKPTEPSVPVQPLLPESLARSLLPSTEYQKQLLAAQVQLQCSPAELQAELLHSQARLAELEAQVRKLELERAQHELLLGSLQQQHQADLELIESAHRSRIKVLETSYQQREERLRRENEELSARYLSQCQEAEQARAELTAQHQRRLAAIAQEKDQEMERLRELQRASILDMRRDHEEQLQRLKLLKDREVDAATSATSHTRSLNSIIHQMEKFSSSLHELSSRVEASHLTTSQERELGIRQRDEQLRALQERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQERWRVTAEQSKAESMQRALEEQRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKERAEREAERALQVDTQREGTLISLAKQAELKIRASELRAEEKQLAAERAALEQERQELRLEKERINATALRVKLRAEEVESMSKVASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHMHQEHLSLAQQRLQLDRARQDLPSSLVGLFPRAQGPAASSQSALMPPAPTTRWCSQPPTGLDPSPLHLHARLALLRHMAEQDRDFLENEQFFLETLKKGSYNLTSHSA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
83
Xenopus
83
Pig
75
Sheep
75
Chicken
75
Bovine
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8TES7 As Substrate

Site PTM Type Enzyme
T27 Phosphorylation
S130 Phosphorylation
S132 Phosphorylation
S134 Phosphorylation
S142 Phosphorylation
T168 Phosphorylation
T180 Phosphorylation
T191 Phosphorylation
T195 Phosphorylation
R247 Methylation
S328 Phosphorylation
S334 Phosphorylation
K340 Acetylation
S359 Phosphorylation
S368 Phosphorylation
T373 Phosphorylation
S375 Phosphorylation
S381 Phosphorylation
S384 Phosphorylation
T385 Phosphorylation
T398 Phosphorylation
S403 Phosphorylation
S408 Phosphorylation
S433 Phosphorylation
S575 Phosphorylation
S756 Phosphorylation
S863 Phosphorylation
S933 Phosphorylation
S1132 Phosphorylation

Research Backgrounds

Function:

Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.

Subcellular Location:

Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome>Centriole. Cytoplasm>Cytoskeleton>Spindle pole. Cell junction.
Note: Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to the apical junction complex (AJC) in epithelial cells.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Present in various epithelial cells (at protein level).

Subunit Structure:

May interact with FAS cytoplasmic domain (By similarity). Interacts with PARD3.

Restrictive clause

 

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