FCRL4 Antibody - #DF10173
| Product: | FCRL4 Antibody |
| Catalog: | DF10173 |
| Description: | Rabbit polyclonal antibody to FCRL4 |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig |
| Mol.Wt.: | 57 kDa; 57kD(Calculated). |
| Uniprot: | Q96PJ5 |
| RRID: | AB_2840752 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10173, RRID:AB_2840752.
Fold/Unfold
CD307d; Fc receptor homolog 4; Fc receptor like 4; Fc receptor like protein 4; Fc receptor-like protein 4; FcR like protein 4; FcR-like protein 4; FcRH4; FcRL4; FCRL4_HUMAN; hIFGP2; IFGP family protein 2; IGFP2; Immune receptor translocation associated protein 1; Immune receptor translocation-associated protein 1; Immunoglobulin superfamily receptor translocation associated 1; Immunoglobulin superfamily receptor translocation associated gene 1; IRTA1;
Immunogens
Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level).
- Q96PJ5 FCRL4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96PJ5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T68 | Phosphorylation | Uniprot | |
| T70 | Phosphorylation | Uniprot | |
| T74 | Phosphorylation | Uniprot | |
| S144 | Phosphorylation | Uniprot | |
| S146 | Phosphorylation | Uniprot | |
| T425 | Phosphorylation | Uniprot | |
| Y451 | Phosphorylation | Uniprot | |
| Y463 | Phosphorylation | Uniprot | |
| Y493 | Phosphorylation | Uniprot | |
| T498 | Phosphorylation | Uniprot |
Research Backgrounds
May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
Phosphorylated on cytoplasmic tyrosines upon activation.
Cell membrane>Single-pass type I membrane protein.
Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level).
Interacts with PTPN6 and PTPN11.
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