C10orf63 Antibody - #DF2906
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2906, RRID:AB_2840895.
Fold/Unfold
Chromosome 10 open reading frame 63; DKFZp781F21103; Enkur; ENKUR_HUMAN; Enkurin; MGC26778;
Immunogens
- Q8TC29 ENKUR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPTCSSECIYNLIPSDLKEPPQPPRYISIFKATVKDDMQKAKTAMKTMGPAKVEVPSPKDFLKKHSKEKTLPPKKNFDRNVPKKPAVPLKTDHPVMGIQSGKNFINTNAADIIMGVAKKPKPIYVDKRTGDKHDLEPSGLVPKYINKKDYGVTPEYICKRNEEIKKAQEDYDRYIQENLKKAAMKRLSDEEREAVLQGLKKNWEEVHKEFQSLSVFIDSIPKKIRKQRLEEEMKQLEHDIGIIEKHKIIYIANNA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8TC29 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y27 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| T44 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| K119 | Acetylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| Y172 | Phosphorylation | Uniprot |
Research Backgrounds
Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.
Cell projection>Cilium>Flagellum.
Note: Sperm acrosomal crescent and flagellar principal piece.
Binds calmodulin via its IQ domain. Interacts with TRPC1, TRPC2, TRPC5, but not TRPC3 (By similarity).
Residues 160-255 contains the TRPC2 binding site.
The IQ motif is involved in calmodulin binding.
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