DNAJC15 Antibody - #DF2918
| Product: | DNAJC15 Antibody |
| Catalog: | DF2918 |
| Description: | Rabbit polyclonal antibody to DNAJC15 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 16kDa; 16kD(Calculated). |
| Uniprot: | Q9Y5T4 |
| RRID: | AB_2840906 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2918, RRID:AB_2840906.
Fold/Unfold
Cell growth inhibiting gene 22 protein; Cell growth-inhibiting gene 22 protein; DJC15_HUMAN; DnaJ (Hsp40) homolog subfamily C member 15; DNAJ domain containing; DnaJ homolog subfamily C member 15; DNAJC15; DNAJD1; GIG22; HSD18; MCJ; Methylation controlled J protein; Methylation-controlled J protein;
Immunogens
- Q9Y5T4 DJC15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAARGVIAPVGESLRYAEYLQPSAKRPDADVDQQRLVRSLIAVGLGVAALAFAGRYAFRIWKPLEQVITETAKKISTPSFSSYYKGGFEQKMSRREAGLILGVSPSAGKAKIRTAHRRVMILNHPDKGGSPYVAAKINEAKDLLETTTKH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y5T4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T77 | Phosphorylation | Uniprot | |
| S79 | Phosphorylation | Uniprot | |
| Y83 | Phosphorylation | Uniprot | |
| S104 | O-Glycosylation | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S106 | O-Glycosylation | Uniprot | |
| S106 | Phosphorylation | Uniprot |
Research Backgrounds
Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.
Mitochondrion inner membrane>Single-pass membrane protein.
Expressed at highest levels in heart, followed by liver and kidney.
Interacts with the TIM23 complex. Directly interacts with PAM16/MAGMAS; this interaction counteracts DNAJC15-dependent stimulation of HSPA9 ATPase activity. Associates with complex I of the mitochondrial electron transfer chain; this interaction may interfere with the formation of supercomplexes that facilitate the transfer of electrons between complexes (By similarity).
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