Product: TMX2 Antibody
Catalog: DF7629
Description: Rabbit polyclonal antibody to TMX2
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 34 kDa; 34kD(Calculated).
Uniprot: Q9Y320
RRID: AB_2841114

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(89%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
TMX2 Antibody detects endogenous levels of total TMX2.
RRID:
AB_2841114
Cite Format: Affinity Biosciences Cat# DF7629, RRID:AB_2841114.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cell proliferation inducing gene 26 protein; Cell proliferation-inducing gene 26 protein; CGI 31; Growth inhibiting gene 11; PDIA12; PIG26; Protein disulfide isomerase family A, member 12; Thioredoxin domain containing protein 14; Thioredoxin domain-containing protein 14; Thioredoxin related transmembrane protein 2; Thioredoxin-related transmembrane protein 2; tmx2; TMX2_HUMAN; TXNDC14;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9Y320 TMX2_HUMAN:

Widely expressed.

Sequence:
MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Rabbit
100
Chicken
89
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y320 As Substrate

Site PTM Type Enzyme
S73 Phosphorylation
K79 Acetylation
S83 Phosphorylation
T85 Phosphorylation
Y132 Phosphorylation
K144 Ubiquitination
T187 Phosphorylation
K193 Ubiquitination
Y206 Phosphorylation
K207 Ubiquitination
T210 Phosphorylation
S211 Phosphorylation
K215 Ubiquitination
K227 Ubiquitination
S243 Phosphorylation
K269 Ubiquitination
S282 Phosphorylation
T283 Phosphorylation
T285 Phosphorylation
T286 Phosphorylation
S288 Phosphorylation
K293 Ubiquitination

Research Backgrounds

Subcellular Location:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed.

Family&Domains:

The thioredoxin domain lacks the 2 redox-active cysteines, suggesting that it lacks thioredoxin activity.

The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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