TUBGCP3 Antibody - #AF0438
| Product: | TUBGCP3 Antibody |
| Catalog: | AF0438 |
| Description: | Rabbit polyclonal antibody to TUBGCP3 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 105kDa; 104kD(Calculated). |
| Uniprot: | Q96CW5 |
| RRID: | AB_2834397 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0438, RRID:AB_2834397.
Fold/Unfold
Gamma-ring complex protein 104 kDa; Gamma-tubulin complex component 3; GCP-3; GCP3; GCP3_HUMAN; h104p; hGCP3; hGrip104; hSpc98; SPBC98; Spc98p; Spindle pole body protein Spc98 homolog; TUBGCP3; Tubulin gamma complex associated protein 3;
Immunogens
- Q96CW5 GCP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKKELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSLLPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTGGTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWLHNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLESSLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILSLVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQSRKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFETSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGILETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFDQIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESIPKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTRGRRSSHT
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96CW5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| Y131 | Phosphorylation | Uniprot | |
| Y132 | Phosphorylation | Uniprot | |
| Y133 | Phosphorylation | Uniprot | |
| R135 | Methylation | Uniprot | |
| T138 | Phosphorylation | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| Y256 | Phosphorylation | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| K267 | Ubiquitination | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| K280 | Ubiquitination | Uniprot | |
| T290 | Phosphorylation | Uniprot | |
| K303 | Ubiquitination | Uniprot | |
| K375 | Ubiquitination | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| Y443 | Phosphorylation | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| K482 | Ubiquitination | Uniprot | |
| K505 | Ubiquitination | Uniprot | |
| K511 | Ubiquitination | Uniprot | |
| S512 | Phosphorylation | Uniprot | |
| S515 | Phosphorylation | Uniprot | |
| K543 | Ubiquitination | Uniprot | |
| Y544 | Phosphorylation | Uniprot | |
| K551 | Ubiquitination | Uniprot | |
| S614 | Phosphorylation | Uniprot | |
| K689 | Ubiquitination | Uniprot | |
| K831 | Ubiquitination | Uniprot | |
| K837 | Ubiquitination | Uniprot | |
| S896 | Phosphorylation | Uniprot | |
| T899 | Phosphorylation | Uniprot | |
| S904 | Phosphorylation | Uniprot | |
| S905 | Phosphorylation | Uniprot |
Research Backgrounds
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
Ubiquitously expressed.
Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. Interacts with CDK5RAP2; the interaction is leading to centrosomal localization of TUBGCP3 and CDK5RAP2. Interacts with NIN (via N-terminus); the interaction may promote recruitment of the gamma-tubulin ring complex to the centrosome (By similarity).
Belongs to the TUBGCP family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.