Acetyl-Lysine Antibody - #DF7729

Product: | Acetyl-Lysine Antibody |
Catalog: | DF7729 |
Description: | Rabbit polyclonal antibody to Acetyl-Lysine |
Application: | WB |
Reactivity: | Human, All |
Uniprot: | |
RRID: | AB_2841197 |
Product Info
Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,All
Clonality:
Polyclonal
Specificity:
Acetyl-Lysine Antibody detects endogenous levels of Acetyl-Lysine Antibody only when acetylated at Lysine Antibody.
RRID:
AB_2841197
Cite Format: Affinity Biosciences Cat# DF7729, RRID:AB_2841197.
Cite Format: Affinity Biosciences Cat# DF7729, RRID:AB_2841197.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Immunogens
Immunogen:
A synthesized peptide derived from human Lysine Antibody around the acetylation site of Lysine Antibody.
References
1). LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44. Neoplasia (New York, N.Y.), 2024
(PubMed: 39128424)
[IF=6.3]
2). Sirt3 Rescues Porphyromonas gingivalis- Impaired Cementogenesis via SOD2 Deacetylation. CELL PROLIFERATION, 2025
[IF=5.9]
3). Resveratrol ameliorates triglyceride accumulation through FXR deacetylation in high glucose-treated HepG2 cells. Journal of Functional Foods, 2023
[IF=3.8]
Application: WB Species: Human Sample: HepG2 cells
Fig. 4. Effect of resveratrol on the acetylation of FXR in HepG2 cells. (A) The interaction of SIRT1 with FXR. (B) The relative protein levels of Ac-FXR in different groups of HepG2 cells detected by IP.
4). GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis. Experimental Cell Research, 2021
(PubMed: 34461110)
[IF=3.3]
Application: WB Species: Human Sample: CRC cells
Fig. 1. GRIM-19 expression is related to CRC progression. (A) Expression of GRIM-19 transcript in CRC tissues versus adjacent normal tissues. The plotted data
are from the GEPIA database. (B and C) Overall survival and disease-free survival among CRC patients with different GRIM-19 levels. The plotted data are from the
GEPIA database. (D and E) The expression of GRIM-19 and p53 in primary normal colorectal (N) and CRC (T) tissues as analyzed by Western blot assays. (F and G)
The expression of GRIM-19 in normal colorectal and CRC tissues was detected by IHC. Bar = 50 μ m. (H) The expression of GRIM-19 in CRC cell lines DLD-1, SW620,
HT15, HCT116 and HCT-8 as analyzed by Western blot assays.
5). Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway. PeerJ, 2022
(PubMed: 35582617)
[IF=2.3]
Restrictive clause
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For Research Use Only.
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