PKA-R2 beta Antibody - #DF7820
| Product: | PKA-R2 beta Antibody |
| Catalog: | DF7820 |
| Description: | Rabbit polyclonal antibody to PKA-R2 beta |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 46 kDa; 46kD(Calculated). |
| Uniprot: | P31323 |
| RRID: | AB_2841268 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF7820, RRID:AB_2841268.
Fold/Unfold
AI451071; AW061005; cAMP dependent protein kinase type II beta regulatory chain; cAMP dependent protein kinase type II beta regulatory subunit; cAMP-dependent protein kinase type II-beta regulatory subunit; H RG363E19.2; KAP3_HUMAN; MGC116401; Pkarb2; PRKAR 2; PRKAR2; PRKAR2B; Protein kinase cAMP dependent regulatory type II beta; RATDNA; RII beta; RII(beta); RIIbeta; WUGSC:H RG363E19.2;
Immunogens
A synthesized peptide derived from human PKA-R2 beta, corresponding to a region within the internal amino acids.
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
- P31323 KAP3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
Research Backgrounds
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Phosphorylated by the activated catalytic chain.
Cytoplasm. Cell membrane.
Note: Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Belongs to the cAMP-dependent kinase regulatory chain family.
Research Fields
· Organismal Systems > Endocrine system > Insulin signaling pathway. (View pathway)
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