Product: MNX1 Antibody
Catalog: DF7864
Description: Rabbit polyclonal antibody to MNX1
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Zebrafish, Bovine, Dog
Mol.Wt.: 41 kDa; 41kD(Calculated).
Uniprot: P50219
RRID: AB_2841295

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Zebrafish(86%), Bovine(82%), Dog(91%)
Clonality:
Polyclonal
Specificity:
MNX1 Antibody detects endogenous levels of total MNX1.
RRID:
AB_2841295
Cite Format: Affinity Biosciences Cat# DF7864, RRID:AB_2841295.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

HB 9; HB9; HLXB 9; HLXB9; Homeo box HB9; Homeobox HB9; Homeobox protein HB9; HOXHB9; MNX1; MNX1_HUMAN; Motor neuron and pancreas homeobox 1; Motor neuron and pancreas homeobox protein 1; Sacral agenesis autosomal dominant (Currarino triad); SCRA 1; SCRA1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P50219 MNX1_HUMAN:

Expressed in lymphoid and pancreatic tissues.

Sequence:
MEKSKNFRIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGGGGGGGGASGGTSGSCSPASSEPPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDEDEDDEDHFPYSNGASVHAASSDCSSEDDSPPPRPSHQPAPQ

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
91
Zebrafish
86
Bovine
82
Xenopus
57
Chicken
45
Pig
44
Horse
0
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P50219 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S77 Phosphorylation P49841 (GSK3B)
S79 Phosphorylation P49841 (GSK3B)
R215 Methylation
K225 Ubiquitination
K240 Ubiquitination
K264 Ubiquitination
Y265 Phosphorylation
S267 Phosphorylation
K322 Ubiquitination
K342 Ubiquitination

Research Backgrounds

Function:

Putative transcription factor involved in pancreas development and function.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in lymphoid and pancreatic tissues.

Research Fields

· Human Diseases > Endocrine and metabolic diseases > Maturity onset diabetes of the young.

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For Research Use Only.
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