TRAPPC2 Antibody - #DF8137
| Product: | TRAPPC2 Antibody |
| Catalog: | DF8137 |
| Description: | Rabbit polyclonal antibody to TRAPPC2 |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus |
| Mol.Wt.: | 16 kDa; 16kD(Calculated). |
| Uniprot: | P0DI81 |
| RRID: | AB_2841472 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8137, RRID:AB_2841472.
Fold/Unfold
hYP38334; MBP 1 interacting protein 2A; MBP-1-interacting protein 2A; MIP 2A; MIP-2A; MIP2A; SEDL; Sedlin; SEDLP; SEDT; Spondyloepiphyseal dysplasia tarda protein; Spondyloepiphyseal dysplasia, late; TPPC2_HUMAN; Trafficking protein particle complex 2; Trafficking protein particle complex subunit 2; TRAPPC2P1; TRS20; ZNF547L;
Immunogens
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes.
- P0DI81 TPC2A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGSFYFVIVGHHDNPVFEMEFLPAGKAESKDDHRHLNQFIAHAALDLVDENMWLSNNMYLKTVDKFNEWFVSAFVTAGHMRFIMLHDIRQEDGIKNFFTDVYDLYIKFSMNPFYEPNSPIRSSAFDRKVQFLGKKHLLS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P0DI81 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S119 | Phosphorylation | Uniprot | |
| K129 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K136 | Ubiquitination | Uniprot |
Research Backgrounds
Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Cytoplasm>Perinuclear region. Endoplasmic reticulum-Golgi intermediate compartment. Nucleus. Cytoplasm.
Note: Localized in perinuclear granular structures.
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes.
Can homodimerize. Component of the multisubunit TRAPP (transport protein particle) complex, which includes TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Interacts with ENO1, PITX1 and SF1.
Belongs to the TRAPP small subunits family. Sedlin subfamily.
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