S100A13 Antibody - #DF8140
Product: | S100A13 Antibody |
Catalog: | DF8140 |
Description: | Rabbit polyclonal antibody to S100A13 |
Application: | WB IF/ICC |
Reactivity: | Human |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
Mol.Wt.: | 11 kDa; 11kD(Calculated). |
Uniprot: | Q99584 |
RRID: | AB_2841475 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8140, RRID:AB_2841475.
Fold/Unfold
Protein S100 A13; Protein S100-A13; S100 calcium binding protein A13; S100 calcium-binding protein A13; S100a13; S10AD_HUMAN;
Immunogens
- Q99584 S10AD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAEPLTELEESIETVVTTFFTFARQEGRKDSLSVNEFKELVTQQLPHLLKDVGSLDEKMKSLDVNQDSELKFNEYWRLIGELAKEIRKKKDLKIRKK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q99584 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
M1 | Acetylation | Uniprot | |
K30 | Ubiquitination | Uniprot | |
S32 | Phosphorylation | Uniprot | |
S34 | Phosphorylation | Uniprot | |
K51 | Ubiquitination | Uniprot | |
S55 | Phosphorylation | Uniprot | |
K59 | Ubiquitination | Uniprot | |
K61 | Ubiquitination | Uniprot | |
S62 | Phosphorylation | Uniprot | |
S69 | Phosphorylation | Uniprot | |
K85 | Acetylation | Uniprot |
Research Backgrounds
Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).
Cytoplasm. Secreted.
Note: Secretion is mediated by exposure to stress and requires copper ions.
Expressed in heart and skeletal muscle.
Homodimer. Part of a copper-dependent multiprotein complex containing S100A13, FGF1 and SYT1. Interacts with FGF1 and SYT1 (By similarity).
Belongs to the S-100 family.
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