CDH10 Antibody - #DF8256
| Product: | CDH10 Antibody |
| Catalog: | DF8256 |
| Description: | Rabbit polyclonal antibody to CDH10 |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 88 kDa; 88kD(Calculated). |
| Uniprot: | Q9Y6N8 |
| RRID: | AB_2841546 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8256, RRID:AB_2841546.
Fold/Unfold
CAD10_HUMAN; Cadherin 10 (T2 cadherin); Cadherin 10 type 2 (T2 cadherin); Cadherin 10 type 2; Cadherin-10; Cadherin10; CDH10; T2 cadherin; T2-cadherin;
Immunogens
Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung.
- Q9Y6N8 CAD10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTIHQFLLLFLFWVCLPHFCSPEIMFRRTPVPQQRILSSRVPRSDGKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPAAIEEKKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKEHDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQNYDYLREWGPRFNKLAEMYGGGESDKDS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y6N8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T29 | Phosphorylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| Y91 | Phosphorylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| T100 | Phosphorylation | Uniprot | |
| Y344 | Phosphorylation | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| Y361 | Phosphorylation | Uniprot | |
| S646 | Phosphorylation | Uniprot | |
| T694 | Phosphorylation | Uniprot | |
| T701 | Phosphorylation | Uniprot | |
| Y779 | Phosphorylation | Uniprot | |
| S784 | Phosphorylation | Uniprot | |
| S788 | Phosphorylation | Uniprot |
Research Backgrounds
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Cell membrane>Single-pass type I membrane protein.
Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung.
Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
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