SEPP1 Antibody - #DF8258
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| Product: | SEPP1 Antibody |
| Catalog: | DF8258 |
| Description: | Rabbit polyclonal antibody to SEPP1 |
| Application: | WB IHC |
| Reactivity: | Human, Rat, Monkey |
| Prediction: | Pig |
| Mol.Wt.: | 43 kDa; 43kD(Calculated). |
| Uniprot: | P49908 |
| RRID: | AB_2841548 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8258, RRID:AB_2841548.
Fold/Unfold
Selenoprotein P; Selenoprotein P plasma 1; Selp; SeP; Sepp1; SEPP1_HUMAN;
Immunogens
A synthesized peptide derived from human SEPP1, corresponding to a region within the internal amino acids.
Made in the liver and heart and secreted into the plasma. It is also found in the kidney.
- P49908 SEPP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWRSLGLALALCLLPSGGTESQDQSSLCKQPPAWSIRDQDPMLNSNGSVTVVALLQASUYLCILQASKLEDLRVKLKKEGYSNISYIVVNHQGISSRLKYTHLKNKVSEHIPVYQQEENQTDVWTLLNGSKDDFLIYDRCGRLVYHLGLPFSFLTFPYVEEAIKIAYCEKKCGNCSLTTLKDEDFCKRVSLATVDKTVETPSPHYHHEHHHNHGHQHLGSSELSENQQPGAPNAPTHPAPPGLHHHHKHKGQHRQGHPENRDMPASEDLQDLQKKLCRKRCINQLLCKLPTDSELAPRSUCCHCRHLIFEKTGSAITUQCKENLPSLCSUQGLRAEENITESCQURLPPAAUQISQQLIPTEASASURUKNQAKKUEUPSN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49908 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N83 | N-Glycosylation | Uniprot | |
| N119 | N-Glycosylation | Uniprot | |
| N128 | N-Glycosylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S266 | Phosphorylation | Uniprot |
Research Backgrounds
Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Phosphorylation sites are present in the extracellular medium.
Secreted.
Note: Passes from plasma into the glomerular filtrate where it is removed by endocytosis mediated by LRP2 in the proximal tubule epithelium.
Made in the liver and heart and secreted into the plasma. It is also found in the kidney.
The C-terminus is not required for endocytic uptake in the proximal tubule epithelium.
Belongs to the selenoprotein P family.
References
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