Product: ORM2 Antibody
Catalog: DF8280
Description: Rabbit polyclonal antibody to ORM2
Application: WB IF/ICC
Reactivity: Human, Rat
Mol.Wt.: 24 kDa; 24kD(Calculated).
Uniprot: P19652
RRID: AB_2841568

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat
Clonality:
Polyclonal
Specificity:
ORM2 Antibody detects endogenous levels of total ORM2.
RRID:
AB_2841568
Cite Format: Affinity Biosciences Cat# DF8280, RRID:AB_2841568.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AGP B'; AGP 2; AGP B; AGP2; Alpha 1 acid glycoprotein 2; Alpha 1 acid glycoprotein type 2; OMD 2; ORM 2; Orosomucoid2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P19652 A1AG2_HUMAN:

Expressed by the liver and secreted in plasma.

Sequence:
MALSWVLTVLSLLPLLEAQIPLCANLVPVPITNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPNKTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKTLMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLCIPRSDVMYTDWKKDKCEPLEKQHEKERKQEEGES

PTMs - P19652 As Substrate

Site PTM Type Enzyme
N33 N-Glycosylation
N56 N-Glycosylation
N72 N-Glycosylation
N93 N-Glycosylation
K179 Acetylation

Research Backgrounds

Function:

Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction.

PTMs:

N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor).

Subcellular Location:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed by the liver and secreted in plasma.

Family&Domains:

Contains a beta-barrel that binds various ligands in its interior.

Belongs to the calycin superfamily. Lipocalin family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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