PCYOX1 Antibody - #DF8332

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Product: PCYOX1 Antibody
Catalog: DF8332
Description: Rabbit polyclonal antibody to PCYOX1
Application: WB
Reactivity: Human, Mouse, Rat
Mol.Wt.: 57 kDa; 57kD(Calculated).
Uniprot: Q9UHG3
RRID: AB_2841603

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
PCYOX1 Antibody detects endogenous levels of total PCYOX1.
RRID:
AB_2841603
Cite Format: Affinity Biosciences Cat# DF8332, RRID:AB_2841603.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EC 1.8.3.5; KIAA0908; PCL1; PCYOX_HUMAN; PCYOX1; Prenylcysteine lyase; Prenylcysteine oxidase 1; Prenylcysteine oxidase precursor;

Immunogens

Immunogen:

A synthesized peptide derived from human PCYOX1, corresponding to a region within the internal amino acids.

Uniprot:

Q9UHG3(PCYOX_HUMAN) >>Visit HPA database.

Gene(ID):
PCYOX1(51449)
Expression:
Q9UHG3 PCYOX_HUMAN:

Ubiquitous.

Sequence:
MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL

Research Backgrounds

Function:

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.

PTMs:

The protein is glycosylated at one or more potential N-glycosylation sites.

Subcellular Location:

Lysosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous.

Family&Domains:

Belongs to the prenylcysteine oxidase family.

Research Fields

· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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