DCTN3 Antibody - #DF8351
| Product: | DCTN3 Antibody |
| Catalog: | DF8351 |
| Description: | Rabbit polyclonal antibody to DCTN3 |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 21 kDa; 21kD(Calculated). |
| Uniprot: | O75935 |
| RRID: | AB_2841616 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8351, RRID:AB_2841616.
Fold/Unfold
DCNT22; DCTN 22; DCTN22; Dctn3; DCTN3_HUMAN; dynactin 3 (p22); dynactin 3; dynactin 3 isoform 1; Dynactin complex subunit 22 kDa subunit; dynactin light chain; Dynactin subunit 3; p22;
Immunogens
Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
- O75935 DCTN3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVPEHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQVKPAEE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75935 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| Y22 | Phosphorylation | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K60 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| Y72 | Phosphorylation | Uniprot | |
| R75 | Methylation | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| Y154 | Phosphorylation | Uniprot | |
| K156 | Ubiquitination | Uniprot |
Research Backgrounds
Together with dynein may be involved in spindle assembly and cytokinesis.
Cytoplasm. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Chromosome>Centromere>Kinetochore. Cytoplasm>Cytoskeleton>Spindle. Cleavage furrow. Midbody.
Note: Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Subunit of dynactin, a multiprotein complex associated with dynein.
Belongs to the dynactin subunit 3 family.
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