ARL4A Antibody - #DF8378
| Product: | ARL4A Antibody |
| Catalog: | DF8378 |
| Description: | Rabbit polyclonal antibody to ARL4A |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 23 kDa; 23kD(Calculated). |
| Uniprot: | P40617 |
| RRID: | AB_2841640 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8378, RRID:AB_2841640.
Fold/Unfold
ADP ribosylation factor like 4; ADP ribosylation factor like 4A; ADP ribosylation factor like GTPase 4A; ADP-ribosylation factor-like protein 4A; ARL 4; ARL4; Arl4a; ARL4A_HUMAN;
Immunogens
- P40617 ARL4A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGNGLSDQTSILSNLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P40617 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K58 | Ubiquitination | Uniprot | |
| T113 | Phosphorylation | Uniprot | |
| K117 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K181 | Acetylation | Uniprot | |
| K188 | Ubiquitination | Uniprot |
Research Backgrounds
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.
Myristoylated.
Cell membrane. Cytoplasm. Nucleus>Nucleolus.
Note: Localization in the nucleolus is dependent by nucleotide binding.
Interacts with CYTH2. Interacts with KPNA2; the interaction is direct. Does not interacts with ARL4A.
Belongs to the small GTPase superfamily. Arf family.
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