GCS beta 2 Antibody - #DF8552
(2)
| Product: | GCS beta 2 Antibody |
| Catalog: | DF8552 |
| Description: | Rabbit polyclonal antibody to GCS beta 2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Mol.Wt.: | 70 kDa; 70kD(Calculated). |
| Uniprot: | O75343 |
| RRID: | AB_2841756 |
Product Info
Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
GCS beta 2 Antibody detects endogenous levels of total GCS beta 2.
RRID:
AB_2841756
Cite Format: Affinity Biosciences Cat# DF8552, RRID:AB_2841756.
Cite Format: Affinity Biosciences Cat# DF8552, RRID:AB_2841756.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
GC SB2; GCS beta 2; Guanylate cyclase 1 soluble beta 2; GUCY1B2;
Immunogens
Immunogen:
Uniprot:
Expression:
Sequence:
- O75343 GCYB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGYDRMLRTLGGNLMEFIENLDALHSYLALSYQEMNAPSFRVERGADGKMFLHYYSDRSGLCHIVPGIIEAVAKDFFDIDVIMDILDMNEEVERTGKKEHVVFLIVQKAHRKMRKTKPKRLQDSQGMERDQEALQAAFLKMKEKYLNVSACPVKKSHWDVVRSIVMFGKGHLMNTFEPIYPERLWIEEKTFCNAFPFHIVFDESLQVKQARVNIQKYVPGLQTQNIQLDEYFSIIHPQVTFNIFSIRRFINSQFVLKTRREMMPVAWQSRTTLKLQGQMIWMESMWCMVYLCSPKLRSLQELEELNMHLSDIAPNDTTRDLILLNQQRLAEIELSNQLERKKEELQVLSKHLAIEKKKTETLLYAMLPKHVANQLREGKKVAAGEFKSCTILFSDVVTFTNICTACEPIQIVNVLNSMYSKFDRLTSVHAVYKVETIGDAYMVVGGVPVPIGNHAQRVANFALGMRISAKEVTNPVTGEPIQLRVGIHTGPVLADVVGDKMPRYCLFGDTVNTASRMESHGLPNKVHLSPTAYRALKNQGFKIIERGEIEVKGKGRMTTYFLIQNLNATEDEIMGRSKTPVDHKGSTQKASLPTTKLQGSVQPSCPEHSSLASWLL
PTMs - O75343 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y291 | Phosphorylation | Uniprot |
Research Backgrounds
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Expressed in gastric signet ring cell carcinoma, but not in the normal stomach.
Subunit Structure:
Heterodimer of an alpha and a beta chain.
Family&Domains:
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Restrictive clause
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For Research Use Only.
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