SP2 Antibody - #DF8721
| Product: | SP2 Antibody |
| Catalog: | DF8721 |
| Description: | Rabbit polyclonal antibody to SP2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 64 kDa; 65kD(Calculated). |
| Uniprot: | Q02086 |
| RRID: | AB_2841925 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8721, RRID:AB_2841925.
Fold/Unfold
Kiaa0048; OTTHUMP00000196580; SP2; SP2_HUMAN; SPECIFICITY PROTEIN 2; Transcription factor Sp2;
Immunogens
- Q02086 SP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSDPQTSMAATAAVSPSDYLQPAASTTQDSQPSPLALLAATCSKIGPPAVEAAVTPPAPPQPTPRKLVPIKPAPLPLSPGKNSFGILSSKGNILQIQGSQLSASYPGGQLVFAIQNPTMINKGTRSNANIQYQAVPQIQASNSQTIQVQPNLTNQIQIIPGTNQAIITPSPSSHKPVPIKPAPIQKSSTTTTPVQSGANVVKLTGGGGNVTLTLPVNNLVNASDTGAPTQLLTESPPTPLSKTNKKARKKSLPASQPPVAVAEQVETVLIETTADNIIQAGNNLLIVQSPGGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASATLPTVPQKPSQNFQIQAAEPTPTQVYIRTPSGEVQTVLVQDSPPATAAATSNTTCSSPASRAPHLSGTSKKHSAAILRKERPLPKIAPAGSIISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQIQLQMEQALAGETQPGEKRRRMACTCPNCKDGEKRSGEQGKKKHVCHIPDCGKTFRKTSLLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHLVTKNL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02086 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T55 | Phosphorylation | Uniprot | |
| T63 | Phosphorylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| T192 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| T238 | Phosphorylation | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| S380 | Phosphorylation | Uniprot | |
| T383 | Phosphorylation | Uniprot | |
| S389 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| K400 | Ubiquitination | Uniprot | |
| T535 | Phosphorylation | Uniprot | |
| T550 | Phosphorylation | Uniprot | |
| S569 | Phosphorylation | Uniprot | |
| K605 | Ubiquitination | Uniprot | |
| K611 | Ubiquitination | Uniprot |
Research Backgrounds
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.
Nucleus.
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In SP2, the motif is inactive.
Belongs to the Sp1 C2H2-type zinc-finger protein family.
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